A1 Refereed original research article in a scientific journal
Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
Authors: Kattainen Salla, Lindahl Anna, Vasankari Tuula, Ollila Henriikka, Volmonen Kirsi, Piirilä Päivi, Kauppi Paula, Paajanen Juuso, Kreivi Hanna-Riikka, Ulenius Linda, Varpula Tero, Aro Miia, Reijula Jere, Hästbacka Johanna
Publisher: BMC
Publication year: 2022
Journal: BMC Pulmonary Medicine
Journal name in source: BMC PULMONARY MEDICINE
Journal acronym: BMC PULM MED
Article number: 243
Volume: 22
Issue: 1
Number of pages: 10
ISSN: 1471-2466
eISSN: 1471-2466
DOI: https://doi.org/10.1186/s12890-022-02023-w(external)
Web address : https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-022-02023-w(external)
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/176089755(external)
Background
The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19.
Methods
Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge.
Results
A restrictive ventilatory defect was found in 35% (23/65) and an impaired diffusing capacity in 52% (32/62) at 6 months. The 6-minute walk distance was reduced in 33% (18/55), and 7% (4/55) of the patients had reduced exercise capacity. Chest X-ray was abnormal in 78% (52/67) at 6 months after hospital discharge.
Conclusion
A significant number of patients had persisting lung function impairment and radiological abnormalities at 6 months after critical COVID-19. Reduced exercise capacity was rare.
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