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Deep learning accurately classifies elbow joint effusion in adult and pediatric radiographs




TekijätHuhtanen Jarno T, Nyman Mikko, Doncenco Dorin, Hamedian Maral, Kawalya Davis, Salminen Leena, Sequeiros Roberto Blanco, Koskinen Seppo K, Pudas Tomi K, Kajander Sami, Niemi Pekka, Hirvonen Jussi, Aronen Hannu J, Jafaritadi Mojtaba

KustantajaNATURE PORTFOLIO

Julkaisuvuosi2022

JournalScientific Reports

Tietokannassa oleva lehden nimiSCIENTIFIC REPORTS

Lehden akronyymiSCI REP-UK

Artikkelin numero 11803

Vuosikerta12

Numero1

Sivujen määrä11

ISSN2045-2322

DOIhttps://doi.org/10.1038/s41598-022-16154-x

Verkko-osoitehttps://www.nature.com/articles/s41598-022-16154-x

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/175998597


Tiivistelmä
Joint effusion due to elbow fractures are common among adults and children. Radiography is the most commonly used imaging procedure to diagnose elbow injuries. The purpose of the study was to investigate the diagnostic accuracy of deep convolutional neural network algorithms in joint effusion classification in pediatric and adult elbow radiographs. This retrospective study consisted of a total of 4423 radiographs in a 3-year period from 2017 to 2020. Data was randomly separated into training (n = 2672), validation (n = 892) and test set (n = 859). Two models using VGG16 as the base architecture were trained with either only lateral projection or with four projections (AP, LAT and Obliques). Three radiologists evaluated joint effusion separately on the test set. Accuracy, precision, recall, specificity, F1 measure, Cohen's kappa, and two-sided 95% confidence intervals were calculated. Mean patient age was 34.4 years (1-98) and 47% were male patients. Trained deep learning framework showed an AUC of 0.951 (95% CI 0.946-0.955) and 0.906 (95% CI 0.89-0.91) for the lateral and four projection elbow joint images in the test set, respectively. Adult and pediatric patient groups separately showed an AUC of 0.966 and 0.924, respectively. Radiologists showed an average accuracy, sensitivity, specificity, precision, F1 score, and AUC of 92.8%, 91.7%, 93.6%, 91.07%, 91.4%, and 92.6%. There were no statistically significant differences between AUC's of the deep learning model and the radiologists (p value > 0.05). The model on the lateral dataset resulted in higher AUC compared to the model with four projection datasets. Using deep learning it is possible to achieve expert level diagnostic accuracy in elbow joint effusion classification in pediatric and adult radiographs. Deep learning used in this study can classify joint effusion in radiographs and can be used in image interpretation as an aid for radiologists.

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Last updated on 2024-26-11 at 15:19