A1 Refereed original research article in a scientific journal

Sleep in Psychotic Disorders: Results From Nationwide SUPER Finland Study




AuthorsCederlöf Erik, Holm Minna, Lähteenvuo Markku, Haaki Willehard, Hietala Jarmo, Häkkinen Katja, Isometsä Erkki, Jukuri Tuomas, Kajanne Risto, Kampman Olli, Kieseppä Tuula, Lahdensuo Kaisla, Lönnqvist Jouko, Männynsalo Teemu, Niemi-Pynttäri Jussi, Suokas Kimmo, Suvisaari Jaana, Tiihonen Jari, Turunen Hannu, Wegelius Asko, Veijola Juha, Palotie Aarno, Paunio Tiina

PublisherOxford University Press

Publication year2022

JournalSchizophrenia Bulletin Open

Journal name in sourceSchizophrenia Bulletin Open

Article numbersgac011

Volume3

Issue1

eISSN2632-7899

DOIhttps://doi.org/10.1093/schizbullopen/sgac011

Web address https://doi.org/10.1093/schizbullopen/sgac011

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/175758858


Abstract

Objective

Characterizing sleep in patients with schizophrenia, schizoaffective disorder, bipolar disorder, and psychotic depression.

Methods

This cross-sectional questionnaire study is based on the SUPER study sample, which is part of the Stanley Global Neuropsychiatric Genomics Initiative. The study is a multicentre, nationwide Finnish study consisting of patients (N = 8 623) both in primary and specialized health care. The main measurements were sleep duration, difficulties initiating sleep, early morning awakenings, and fatigue. These results were compared with a nationally representative sample of the Finnish population from the Health 2000 survey (N = 7 167) with frequency and logistic regression analyses.

Results

Patients had more sleep problems compared with the general population, especially young and middle-aged patients (Difficulties initiating sleep in young patients odds ratio = 12.3, 95% CI 9.8–15.4). Long sleep duration was the most deviating property of the sleep characteristics, being particularly common among young patients with schizophrenia (odds ratio = 27.9, 95% CI 22.1–35.2, 47.4% vs 3.3% prevalence). All sleep problems were associated with worse subjective health. We also conducted a latent class analysis, resulting in a cluster relatively free of sleep problems (58% of patients), an insomnia symptom cluster (26%), and a hypersomnia symptom cluster (15%).

Conclusions

In our sample, patients with psychotic disorders have more sleep problems—especially long sleep duration but also insomnia symptoms—compared with the general population. The patients can in a latent class analysis of their sleep symptoms be divided into groups with differing sleep profiles.


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Last updated on 2024-26-11 at 22:43