A1 Refereed original research article in a scientific journal
Similarity Index for the Fat Fraction between Breast Milk and Infant Formulas
Authors: Hokkanen Sanna, Frey Alexander D, Yang Baoru, Linderborg Kaisa M
Publisher: AMER CHEMICAL SOC
Publication year: 2022
Journal: Journal of Agricultural and Food Chemistry
Journal name in source: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Journal acronym: J AGR FOOD CHEM
Volume: 70
Issue: 20
First page : 6191
Last page: 6201
Number of pages: 11
ISSN: 0021-8561
eISSN: 1520-5118
DOI: https://doi.org/10.1021/acs.jafc.1c08029
Web address : https://pubs.acs.org/doi/10.1021/acs.jafc.1c08029
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/175748114
The similarity of the fat fraction in infant formulas rich in either bovine milk fat (MF) or vegetable oil (VO) to breastmilk was evaluated by analyzing their lipid composition. Milk fat-rich formulas were highly similar (average similarity index 0.68) tobreast milk compared to the VO-rich formulas (average similarity index 0.56). The highest difference in the indices was found in thecontents of cholesterol (0.66 vs 0.28 in MF- and VO-rich formulas, respectively, on average) and polar lipids (0.84 vs 0.53), thepositional distribution of fatty acids in thesn-2 position of triacylglycerols (0.53 vs 0.28), and fatty acid composition (0.72 vs 0.54).The VO-based formulas were superior in similarity inn-6 PUFA. Thus, the addition of bovine MF fractions is an effective way toincrease the similarity between the lipid composition of infant formulas and human milk
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