A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Real-time eye motion correction in phase-resolved OCT angiography with tracking SLO
Tekijät: Braaf B, Vienola KV, Sheehy CK, Yang Q, Vermeer KA, Tiruveedhula P, Arathorn DW, Roorda A, de Boer JF
Kustantaja: Optical Society of America
Julkaisuvuosi: 2013
Journal: Biomedical Optics Express
Tietokannassa oleva lehden nimi: BIOMEDICAL OPTICS EXPRESS
Lehden akronyymi: Biomed. Opt. Express
Vuosikerta: 4
Numero: 1
Aloitussivu: 51
Lopetussivu: 65
Sivujen määrä: 15
ISSN: 2156-7085
DOI: https://doi.org/10.1364/BOE.4.000051
Verkko-osoite: https://opg.optica.org/boe/fulltext.cfm?uri=boe-4-1-51
Tiivistelmä
In phase-resolved OCT angiography blood flow is detected from phase changes in between A-scans that are obtained from the same location. In ophthalmology, this technique is vulnerable to eye motion. We address this problem by combining inter-B-scan phase-resolved OCT angiography with real-time eye tracking. A tracking scanning laser ophthalmoscope (TSLO) at 840 nm provided eye tracking functionality and was combined with a phase-stabilized optical frequency domain imaging (OFDI) system at 1040 nm. Real-time eye tracking corrected eye drift and prevented discontinuity artifacts from (micro) saccadic eye motion in OCT angiograms. This improved the OCT spot stability on the retina and consequently reduced the phase-noise, thereby enabling the detection of slower blood flows by extending the inter-B-scan time interval. In addition, eye tracking enabled the easy compounding of multiple data sets from the fovea of a healthy volunteer to create high-quality eye motion artifact-free angiograms. High-quality images are presented of two distinct layers of vasculature in the retina and the dense vasculature of the choroid. Additionally we present, for the first time, a phase-resolved OCT angiogram of the mesh-like network of the choriocapillaris containing typical pore openings. (C) 2012 Optical Society of America
In phase-resolved OCT angiography blood flow is detected from phase changes in between A-scans that are obtained from the same location. In ophthalmology, this technique is vulnerable to eye motion. We address this problem by combining inter-B-scan phase-resolved OCT angiography with real-time eye tracking. A tracking scanning laser ophthalmoscope (TSLO) at 840 nm provided eye tracking functionality and was combined with a phase-stabilized optical frequency domain imaging (OFDI) system at 1040 nm. Real-time eye tracking corrected eye drift and prevented discontinuity artifacts from (micro) saccadic eye motion in OCT angiograms. This improved the OCT spot stability on the retina and consequently reduced the phase-noise, thereby enabling the detection of slower blood flows by extending the inter-B-scan time interval. In addition, eye tracking enabled the easy compounding of multiple data sets from the fovea of a healthy volunteer to create high-quality eye motion artifact-free angiograms. High-quality images are presented of two distinct layers of vasculature in the retina and the dense vasculature of the choroid. Additionally we present, for the first time, a phase-resolved OCT angiogram of the mesh-like network of the choriocapillaris containing typical pore openings. (C) 2012 Optical Society of America
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