A3 Refereed book chapter or chapter in a compilation book
In Vivo Imaging of Brown Adipose Tissue in Humans: FDG-PET/CT and Beyond
Authors: Virtanen Kirsi A
Editors: Guertin Davia A, Wolfrum Christian
Publisher: Humana Press Inc.
Publishing place: New York
Publication year: 2022
Book title : Brown adipose tissue
Journal name in source: Methods in Molecular Biology
Series title: Methods in Molecular Biology
Volume: 2448
First page : 283
Last page: 289
ISBN: 978-1-0716-2086-1
eISBN: 978-1-0716-2087-8
ISSN: 1064-3745
DOI: https://doi.org/10.1007/978-1-0716-2087-8_18
Web address : https://link.springer.com/protocol/10.1007/978-1-0716-2087-8_18
Positron emission tomography (PET) combined with computed tomography (CT) is used to detect brown adipose tissue (BAT) in humans. Function can be measured using different tracers, most typically with glucose analog 18F-fluoro-deoxyglucose (FDG). CT provides an anatomical reference, but this tool can be utilized for other purposes as well, such as indirect estimate of triglyceride content of the BAT. PET/CT measurements require sophisticated and highly specified devices, and manufacturer-dependent differences exist between different scanners. Therefore, complete device-specific instructions are not given in this article, but rather general guidelines which are important when human BAT is imaged using PET/CT.
