A1 Refereed original research article in a scientific journal
Novel heterocyst-specific flavodiiron proteins in Anabaena sp PCC 7120
Authors: Ermakova M, Battchikova N, Allahverdiyeva Y, Aro EM
Publisher: ELSEVIER SCIENCE BV
Publishing place: Laboratory of Molecular Plant Biology, Department of Biochemistry and Food Chemistry, University of Turku, FI-20014 Turku, Finland
Publication year: 2013
Journal: FEBS Letters
Journal name in source: FEBS LETTERS
Journal acronym: FEBS LETT
Number in series: 1
Volume: 587
Issue: 1
First page : 82
Last page: 87
Number of pages: 6
ISSN: 0014-5793
eISSN: 1873-3468
DOI: https://doi.org/10.1016/j.febslet.2012.11.006
Web address : 10.1016/j.febslet.2012.11.006
Abstract
Flavodiiron proteins present in many prokaryotic and some eukaryotic organisms have a capacity to protect cells against nitrosative or oxidative stress. In Anabaena sp. PCC 7120, Flv1 and Flv3 proteins are encoded by families of two genes. We demonstrate here that flv1A and flv3A genes are up-regulated in vegetative cells in low CO2 and high light conditions. In contrast, flv1B and flv3B genes are expressed in N-2-fixing conditions and corresponding proteins are located exclusively in heterocysts. It is suggested that Flv1B and Flv3B protect enzymes of N-2-fixation in heterocysts of Anabaena 7120 by reducing molecular oxygen directly to water. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
Flavodiiron proteins present in many prokaryotic and some eukaryotic organisms have a capacity to protect cells against nitrosative or oxidative stress. In Anabaena sp. PCC 7120, Flv1 and Flv3 proteins are encoded by families of two genes. We demonstrate here that flv1A and flv3A genes are up-regulated in vegetative cells in low CO2 and high light conditions. In contrast, flv1B and flv3B genes are expressed in N-2-fixing conditions and corresponding proteins are located exclusively in heterocysts. It is suggested that Flv1B and Flv3B protect enzymes of N-2-fixation in heterocysts of Anabaena 7120 by reducing molecular oxygen directly to water. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
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