A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The Cholinergic Potential, the Vagus Nerve and Challenges in Treatment of Traumatic Brain Injury
Tekijät: Uteshev VV, Tenovuo O, Gaidhani N
Kustantaja: BENTHAM SCIENCE PUBL LTD
Julkaisuvuosi: 2016
Journal: Current Pharmaceutical Design
Tietokannassa oleva lehden nimi: CURRENT PHARMACEUTICAL DESIGN
Lehden akronyymi: CURR PHARM DESIGN
Vuosikerta: 22
Numero: 14
Aloitussivu: 2083
Lopetussivu: 2092
Sivujen määrä: 10
ISSN: 1381-6128
eISSN: 1873-4286
DOI: https://doi.org/10.2174/1381612822666160127111630
Tiivistelmä
Existing treatments of traumatic brain injury (TBI) have failed to reverse tremendous losses in productivity, independence and overall quality of life among TBI victims and therefore, cannot be viewed as sufficient. Although there is no shortage of promising basic concepts that may translate to efficacious therapies after TBI, the accumulated knowledge has yet to deliver treatments that adequately meet clinical and social demands. In this article, we discuss novel concepts, recent advances and accompanying challenges in developing cholinergic and related therapies after TBI.
Existing treatments of traumatic brain injury (TBI) have failed to reverse tremendous losses in productivity, independence and overall quality of life among TBI victims and therefore, cannot be viewed as sufficient. Although there is no shortage of promising basic concepts that may translate to efficacious therapies after TBI, the accumulated knowledge has yet to deliver treatments that adequately meet clinical and social demands. In this article, we discuss novel concepts, recent advances and accompanying challenges in developing cholinergic and related therapies after TBI.
Turun yliopiston Tutkimustietojärjestelmän portaali