Influenza A Induced Acute Autonomic Neuropathy in an Adolescent



: Lukkarinen H, Peltola V

Publisher: ELSEVIER SCIENCE INC

: 2010

: Pediatric Neurology

: PEDIATRIC NEUROLOGY

: PEDIATR NEUROL

: 6

: 43

: 6

: 425

: 426

: 2

: 0887-8994

DOI: https://doi.org/10.1016/j.pediatrneurol.2010.06.011


Influenza A may cause serious neurologic complications, but an autoimmune autonomic ganglionopathy has rarely been reported. Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction. A 15-year-old girl developed severe and persisting orthostatic hypotension during influenza A infection. Removal of circulating antibodies by a single course of intravenous immunoglobulin resulted in rapid and complete recovery. (C) 2010 by Elsevier Inc. All rights reserved.



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