A1 Refereed original research article in a scientific journal
Influenza A Induced Acute Autonomic Neuropathy in an Adolescent
Authors: Lukkarinen H, Peltola V
Publisher: ELSEVIER SCIENCE INC
Publication year: 2010
Journal: Pediatric Neurology
Journal name in source: PEDIATRIC NEUROLOGY
Journal acronym: PEDIATR NEUROL
Number in series: 6
Volume: 43
Issue: 6
First page : 425
Last page: 426
Number of pages: 2
ISSN: 0887-8994
DOI: https://doi.org/10.1016/j.pediatrneurol.2010.06.011
Abstract
Influenza A may cause serious neurologic complications, but an autoimmune autonomic ganglionopathy has rarely been reported. Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction. A 15-year-old girl developed severe and persisting orthostatic hypotension during influenza A infection. Removal of circulating antibodies by a single course of intravenous immunoglobulin resulted in rapid and complete recovery. (C) 2010 by Elsevier Inc. All rights reserved.
Influenza A may cause serious neurologic complications, but an autoimmune autonomic ganglionopathy has rarely been reported. Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction. A 15-year-old girl developed severe and persisting orthostatic hypotension during influenza A infection. Removal of circulating antibodies by a single course of intravenous immunoglobulin resulted in rapid and complete recovery. (C) 2010 by Elsevier Inc. All rights reserved.
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