Pharmacokinetics of Intravenous Paracetamol in Elderly Patients

: Liukas A, Kuusniemi K, Aantaa R, Virolainen P, Niemi M, Neuvonen PJ, Olkkola KT

Publisher: ADIS INT LTD

: 2011

: Clinical Pharmacokinetics

: CLINICAL PHARMACOKINETICS

: CLIN PHARMACOKINET

: 2

: 50

: 2

: 121

: 129

: 9

: 0312-5963

DOI: https://doi.org/10.2165/11537240-000000000-00000

Conclusion: Age and sex are important factors affecting the pharmacokinetics of paracetamol. The higher the age of the patient, the higher is the exposure to paracetamol. Female sex is associated with increased paracetamol concentrations but ABCG2 genotype does not seem to affect paracetamol pharmacokinetics.