A1 Refereed original research article in a scientific journal
Pharmacokinetics of Intravenous Paracetamol in Elderly Patients
Authors: Liukas A, Kuusniemi K, Aantaa R, Virolainen P, Niemi M, Neuvonen PJ, Olkkola KT
Publisher: ADIS INT LTD
Publication year: 2011
Journal: Clinical Pharmacokinetics
Journal name in source: CLINICAL PHARMACOKINETICS
Journal acronym: CLIN PHARMACOKINET
Number in series: 2
Volume: 50
Issue: 2
First page : 121
Last page: 129
Number of pages: 9
ISSN: 0312-5963
DOI: https://doi.org/10.2165/11537240-000000000-00000
Abstract
Conclusion: Age and sex are important factors affecting the pharmacokinetics of paracetamol. The higher the age of the patient, the higher is the exposure to paracetamol. Female sex is associated with increased paracetamol concentrations but ABCG2 genotype does not seem to affect paracetamol pharmacokinetics.
Conclusion: Age and sex are important factors affecting the pharmacokinetics of paracetamol. The higher the age of the patient, the higher is the exposure to paracetamol. Female sex is associated with increased paracetamol concentrations but ABCG2 genotype does not seem to affect paracetamol pharmacokinetics.
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