Phenolic Compounds from Eucalyptus gomphocephala with Potential Cytotoxic and Antioxidant Activities



: Al-Sayed E, Martiskainen O, Bobrowska-Hagerstrand M, Sinkkonen J, Tornquist K, Pihlaja K, Ayoub N, Singab AN

Publisher: NATURAL PRODUCTS INC

: 2010

: Natural Product Communications

: NATURAL PRODUCT COMMUNICATIONS

: NAT PROD COMMUN

: 10

: 5

: 10

: 1639

: 1642

: 4

: 1934-578X


Two new phenolic compounds, 2,4,6-trihydroxy-5-methyl-acetophenone 2-O-beta-D-glucopyranoside (3), and benzyl alcohol 7-O-(3',4',6'-tri-O-galloyl)-beta-D-glucopyranoside (8), together with eight known phenolic compounds, were isolated from the 70% aqueous acetone extract of Eucalyptus gomphocephala DC. (Myrtaceae). The isolated compounds were elucidated based on their (1)H, (13)C, DQF-COSY, selective 1D-TOCSY, HSQC, and HMBC NMR spectroscopic and ESI-MS data. The antioxidant effect of the phenolic compounds was tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical and super oxide anion radical scavenging assays. The cytotoxicity of the isolated compounds was evaluated using HeLa cell line.



Last updated on 2024-26-11 at 21:45