Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere Vascular Study



: Niinisalo P, Oksala N, Levula M, Pelto-Huikko M, Jarvinen O, Salenius JP, Kytomaki L, Soini JT, Kahonen M, Laaksonen R, Hurme M, Lehtimaki T

Publisher: INFORMA HEALTHCARE

: 2010

: Annals of Medicine

: ANNALS OF MEDICINE

: ANN MED

: 1

: 42

: 1

: 55

: 63

: 9

: 0785-3890

DOI: https://doi.org/10.3109/07853890903321559


Conclusions. IDO and the IDO-related pathway are important mediators of the immunoinflammatory responses in advanced atherosclerosis offering new viable therapeutic targets for the development of antiatherogenic immunosuppressive therapies.




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