Investigation of Solid Phase Composition on Tablet Surfaces by Grazing Incidence X-ray Diffraction



: Koradia V, Tenho M, de Diego HL, Ringkjobing-Elema M, Moller-Sonnergaard J, Salonen J, Lehto VP, Rantanen J

Publisher: SPRINGER/PLENUM PUBLISHERS

: 2012

: Pharmaceutical Research

: PHARMACEUTICAL RESEARCH

: PHARM RES-DORDR

: 1

: 29

: 1

: 134

: 144

: 11

: 0724-8741

DOI: https://doi.org/10.1007/s11095-011-0520-8


With GIXD measurements, it was possible to probe the solid form composition at the different depths of the tablet surfaces and to obtain depth-dependent information on the compaction-induced amorphization, crystal disordering and dehydration.



Last updated on 2024-26-11 at 14:57