A1 Refereed original research article in a scientific journal
Investigation of Solid Phase Composition on Tablet Surfaces by Grazing Incidence X-ray Diffraction
Authors: Koradia V, Tenho M, de Diego HL, Ringkjobing-Elema M, Moller-Sonnergaard J, Salonen J, Lehto VP, Rantanen J
Publisher: SPRINGER/PLENUM PUBLISHERS
Publication year: 2012
Journal: Pharmaceutical Research
Journal name in source: PHARMACEUTICAL RESEARCH
Journal acronym: PHARM RES-DORDR
Number in series: 1
Volume: 29
Issue: 1
First page : 134
Last page: 144
Number of pages: 11
ISSN: 0724-8741
DOI: https://doi.org/10.1007/s11095-011-0520-8
Abstract
With GIXD measurements, it was possible to probe the solid form composition at the different depths of the tablet surfaces and to obtain depth-dependent information on the compaction-induced amorphization, crystal disordering and dehydration.
With GIXD measurements, it was possible to probe the solid form composition at the different depths of the tablet surfaces and to obtain depth-dependent information on the compaction-induced amorphization, crystal disordering and dehydration.