A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Pregnancy Complications Following Prenatal Exposure to SSRIs or Maternal Psychiatric Disorders: Results From Population-Based National Register Data
Tekijät: Malm H, Sourander A, Gissler M, Gyllenberg D, Hinkka-Yli-Salomaki S, McKeague IW, Artama M, Brown AS
Kustantaja: AMER PSYCHIATRIC PUBLISHING, INC
Julkaisuvuosi: 2015
Journal: American Journal of Psychiatry
Tietokannassa oleva lehden nimi: AMERICAN JOURNAL OF PSYCHIATRY
Lehden akronyymi: AM J PSYCHIAT
Vuosikerta: 172
Numero: 12
Aloitussivu: 1224
Lopetussivu: 1232
Sivujen määrä: 9
ISSN: 0002-953X
DOI: https://doi.org/10.1176/appi.ajp.2015.14121575
Conclusions: In a large national birth cohort, treatment of maternal psychiatric disorders with SSRIs during pregnancy was related to a lower risk of preterm birth and cesarean section but a higher risk of neonatal maladaptation. The findings provide novel evidence for a protective rote of SSRIs on some deleterious reproductive outcomes, possibly by reducing maternal depressive symptoms. The divergent findings suggest that clinical decisions on SSRI use during pregnancy should be individualized, taking into account the mother's psychiatric and reproductive history.
