Impact of gender, apolipoprotein E phenotypes, and diet on serum lipids and lipoproteins in infancy




Lapinleimu H, Viikari J, Niinikoski H, Tuominen J, Ronnemaa T, Valimaki I, Marniemi J, Jokinen E, Ehnholm C, Simell O

PublisherMOSBY-ELSEVIER

1997

 Journal of Pediatrics

JOURNAL OF PEDIATRICS

J PEDIATR-US

131

6

825

832

8

0022-3476

DOIhttps://doi.org/10.1016/S0022-3476(97)70028-3



Conclusions: At 7 months of age diet is an important predictor of serum lipid and lipoprotein concentrations. At the age of 13 months the apolipoprotein E phenotype significantly predicts the concentrations of serum non-high-density lipoprotein cholesterol and apolipoprotein B. However, at both ages apolipoprotein E phenotype, gender, and diet together explain only from 1.4% to 15.5% of the variance in serum lipids and apolipoproteins, suggesting that other, presumably genetic, factors are major determinants.




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