Impact of gender, apolipoprotein E phenotypes, and diet on serum lipids and lipoproteins in infancy
: Lapinleimu H, Viikari J, Niinikoski H, Tuominen J, Ronnemaa T, Valimaki I, Marniemi J, Jokinen E, Ehnholm C, Simell O
Publisher: MOSBY-ELSEVIER
: 1997
Journal of Pediatrics
: JOURNAL OF PEDIATRICS
: J PEDIATR-US
: 131
: 6
: 825
: 832
: 8
: 0022-3476
DOI: https://doi.org/10.1016/S0022-3476(97)70028-3
Conclusions: At 7 months of age diet is an important predictor of serum lipid and lipoprotein concentrations. At the age of 13 months the apolipoprotein E phenotype significantly predicts the concentrations of serum non-high-density lipoprotein cholesterol and apolipoprotein B. However, at both ages apolipoprotein E phenotype, gender, and diet together explain only from 1.4% to 15.5% of the variance in serum lipids and apolipoproteins, suggesting that other, presumably genetic, factors are major determinants.