Impact of gender, apolipoprotein E phenotypes, and diet on serum lipids and lipoproteins in infancy - UTU Research Portal

A1 Refereed original research article in a scientific journal

Impact of gender, apolipoprotein E phenotypes, and diet on serum lipids and lipoproteins in infancy

Authors: Lapinleimu H, Viikari J, Niinikoski H, Tuominen J, Ronnemaa T, Valimaki I, Marniemi J, Jokinen E, Ehnholm C, Simell O

Publisher: MOSBY-ELSEVIER

Publication year: 1997

Journal:: Journal of Pediatrics

Journal name in source: JOURNAL OF PEDIATRICS

Journal acronym: J PEDIATR-US

Volume: 131

Issue: 6

First page : 825

Last page: 832

Number of pages: 8

ISSN: 0022-3476

DOI: https://doi.org/10.1016/S0022-3476(97)70028-3

Abstract

Conclusions: At 7 months of age diet is an important predictor of serum lipid and lipoprotein concentrations. At the age of 13 months the apolipoprotein E phenotype significantly predicts the concentrations of serum non-high-density lipoprotein cholesterol and apolipoprotein B. However, at both ages apolipoprotein E phenotype, gender, and diet together explain only from 1.4% to 15.5% of the variance in serum lipids and apolipoproteins, suggesting that other, presumably genetic, factors are major determinants.