A1 Journal article – refereed

Fish scales and SNP chips: SNP genotyping and allele frequency estimation in individual and pooled DNA from historical samples of Atlantic salmon (Salmo salar)

List of Authors: Johnston SE, Lindqvist M, Niemela E, Orell P, Erkinaro J, Kent MP, Lien S, Vaha JP, Vasemagi A, Primmer CR


Publication year: 2013

Journal: BMC Genomics

Journal name in source: BMC GENOMICS

Journal acronym: BMC GENOMICS

Number in series: 439

Volume number: 14

Issue number: 439

Number of pages: 13

ISSN: 1471-2164

DOI: http://dx.doi.org/10.1186/1471-2164-14-439

Conclusions: SNP genotyping was highly successful in degraded DNA samples, paving the way for the use of degraded samples in SNP genotyping projects. DNA pooling provides the potential for large scale population genetic studies with fewer assays, provided enough reference individuals are also genotyped and DNA quality is properly assessed beforehand. We provide recommendations for future studies intending to conduct high-throughput SNP genotyping and allele frequency estimation in historical samples.

Last updated on 2021-24-06 at 09:57