A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The distribution of collagen types I, III, and IV in normal and malignant colorectal mucosa
Tekijät: Hilska M, Collan Y, Peltonen J, Gullichsen R, Paajanen H, Laato M
Kustantaja: SCANDINAVIAN UNIVERSITY PRESS
Julkaisuvuosi: 1998
Lehti:: European Journal of Surgery
Tietokannassa oleva lehden nimi: EUROPEAN JOURNAL OF SURGERY
Lehden akronyymi: EUR J SURG
Vuosikerta: 164
Numero: 6
Aloitussivu: 457
Lopetussivu: 464
Sivujen määrä: 8
ISSN: 1102-4151
Tiivistelmä
Conclusion: Both the epithelial basement membrane and the collagenous matrix immediately beneath it are degraded in malignant tissue. This may suggest the simultaneous activation of several degradative enzymes las type I and II collagens are at least in part degraded by different enzymes from type TV collagen) or alterations in the expression of collagen subtypes in normal compared with malignant tissue.
Conclusion: Both the epithelial basement membrane and the collagenous matrix immediately beneath it are degraded in malignant tissue. This may suggest the simultaneous activation of several degradative enzymes las type I and II collagens are at least in part degraded by different enzymes from type TV collagen) or alterations in the expression of collagen subtypes in normal compared with malignant tissue.
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