A1 Refereed original research article in a scientific journal

The distribution of collagen types I, III, and IV in normal and malignant colorectal mucosa




AuthorsHilska M, Collan Y, Peltonen J, Gullichsen R, Paajanen H, Laato M

PublisherSCANDINAVIAN UNIVERSITY PRESS

Publication year1998

Journal:European Journal of Surgery

Journal name in sourceEUROPEAN JOURNAL OF SURGERY

Journal acronymEUR J SURG

Volume164

Issue6

First page 457

Last page464

Number of pages8

ISSN1102-4151


Abstract
Conclusion: Both the epithelial basement membrane and the collagenous matrix immediately beneath it are degraded in malignant tissue. This may suggest the simultaneous activation of several degradative enzymes las type I and II collagens are at least in part degraded by different enzymes from type TV collagen) or alterations in the expression of collagen subtypes in normal compared with malignant tissue.



Last updated on 2025-13-10 at 13:34