Johanna Hynninen
Adjunct professor, MD, Gynecologic oncologist
gynaecologic oncology; ovarian cancer
https://sites.utu.fi/ovariancancer/ https://www.deciderproject.eu
- Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma (2023) Lahtinen Alexandra, Lavikka Kari, Virtanen Anni, Li Yilin, Jamalzadeh Sanaz, Skorda Aikaterini, Lauridsen Anna Rössberg, Zhang Kaiynag, Marchi Giovanni, Isoviita Veli-Matti, Ariotta Valeria, Lehtonen Oskari, Muranen Taru A., Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Senkowski Wojciech, Kallunki Tuula, Häkkinen Aantti, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa
- Evolutionary study identifies poor prognosis HGSC patients and reveals clinically relevant targets at diagnosis and relapse (2023)
- International Journal of Gynecological Cancer
Oikkonen, Jaana; Lahtinen, Alexandra; Lavikka, Kari; Virtanen, Anni; Li, Yilin; Jamalzadeh, Sanaz; Skorda, Aikaterini; Lauridsen, Anna Rossberg; Zhang, Kaiyang; Marchi, Giovanni; Nguyen, Mai T. N.; Rajavuori, Anna; Muranen, Taru A.; Huhtinen, Kaisa; Hietanen, Sakari; Senkowski, Wojciech; Kallunki, Tuula; Hakkinen, Antti; Hynninen, Johanna; Hautaniemi, Sampsa
- Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes (2023) Pikkusaari Sanna, Tumiati Manuela, Virtanen Anni, Oikkonen Jaana, Li Yilin, Perez-Villatoro Fernando, Muranen Taru, Salko Matilda, Huhtinen Kaisa, Kanerva Anna, Koskela Heidi, Tapper Johanna, Koivisto-Korander Riitta, Joutsiniemi Titta, Haltia Ulla-Maija, Lassus Heini, Hautaniemi Sampsa, Färkkilä Anniina, Hynninen Johanna, Hietanen Sakari, Carpen Olli, Kauppi Liisa
- H&E image analysis pipeline for quantifying morphological features (2023)
- Journal of Pathology Informatics
Ariotta Valeria, Lehtonen Oskari, Salloum Shams, Micoli Giulia, Lavikka Kari, Rantanen Ville, Hynninen Johanna, Virtanen Anni, Hautaniemi Sampsa
- Multi-omics characterization of chemo-refractory high-grade serous cancer (2023)
- International Journal of Gynecological Cancer
Muranen, Taru A.; Afenteva, Daria; Rajavuori, Anna; Jamalzadeh, Sanaz; Zhang, Kaiyang; Ariotta, Valeria; Isoviita, Veli-Matti; Lahtinen, Alexandra; Lavikka, Kari; Lehtonen, Oskari; Li, Yilin; Marchi, Giovanni; Oikkonen, Jaana; Salloum, Shams; Huhtinen, Kaisa; Hietanen, Sakari; Virtanen, Anni; Hynninen, Johanna; Hautaniemi, Sampsa
- Quantification of cell death and proliferation of patient-derived ovarian cancer organoids through 3D imaging and image analysis (2023) Skorda Aikaterini, Lauridsen Anna Rossberg, Huhtinen Kaisa, Lahtinen Alexandra, Senkowski Wojciech, Oikkonen Jaana, Hynninen Johanna, Hautaniemi Sampsa, Kallunki Tuula
- Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high-grade serous ovarian cancer (2023)
- Basic and Clinical Pharmacology and Toxicology
Deng Feng, Laasik Maren, Salminen Liina, Lapatto Lauri, Huhtinen Kaisa, Li Yilin, Hautaniemi Sampsa, Hynninen Johanna, Niemi Mikko, Lehtonen Rainer
- A Subset of Secreted Proteins in Ascites Can Predict Platinum-Free Interval in Ovarian Cancer (2022) Carroll Molly J, Kaipio Katja, Hynninen Johanna, Carpen Olli, Hautaniemi Sampsa, Page David, Kreeger Pamela K
- Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status (2022) Roering Pia, Siddiqui Arafat, Heuser Vanina D, Potdar Swapnil, Mikkonen Pia, Oikkonen Jaana, Li Yilin, Pikkusaari Sanna, Wennerberg Krister, Hynninen Johanna, Grenman Seija, Huhtinen Kaisa, Auranen Annika, Carpén Olli, Kaipio Katja
- Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer (2022) Zhang Kaiyang, Erkan Erdogan Pekcan, Jamalzadeh Sanaz, Dai Jun, Andersson Noora, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Oikkonen Jaana, Hynninen Johanna, Virtanen Anni, Häkkinen Antti, Hautaniemi Sampsa, Vähärautio Anna
- Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer (2022) Perez-Villatoro Fernando, Oikkonen Jaana, Casado Julia, Chernenko Anastasiya, Gulhan Doga C., Tumiati Manuela, Li Yilin, Lavikka Kari, Hietanen Sakari, Hynninen Johanna, Haltia Ulla-Maija, Tyrmi Jaakko S., Laivuori Hannele, Konstantinopoulos Panagiotis A., Hautaniemi Sampsa, Kauppi Liisa, Färkkilä Anniina
- QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability (2022) Jamalzadeh Sanaz, Häkkinen Antti, Andersson Noora, Huhtinen Kaisa, Laury Anna, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Carpén Olli, Virtanen Anni, Hautaniemi Sampsa
- Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality (2021) Jukonen Joonas, Moyano-Galceran Lidia, Höpfner Katrin, Pietilä Elina A, Lehtinen Laura, Huhtinen Kaisa, Gucciardo Erica, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Ojala Päivi M, Carpén Olli, Lehti Kaisa
- Agile Workflow For Interactive Analysis Of Mass Cytometry Data (2021) Casado J, Lehtonen O, Rantanen V, Kaipio K, Pasquini L, Häkkinen A, Petrucci E, Hynninen J, Hietanen S, Carpén O, Biffoni M, Färkkilä A, Hautaniemi S
- A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer (2021) Salminen Liina, Braicu EIena, Lääperi Mitja, Jylhä Antti, Oksa Sinikka, Hietanen Sakari, Sehouli Jalid, Kulbe Hagen, du Bois Andras du, Mahner Sven, Harter Philipp, Carpen Oolli, Huhtinen Kaisa, Hynninen Johanna, Hilvo Mika
- Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021) Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
- Diagnostic efficiency of whole-body 18F-FDG PET/MRI, MRI alone, and SUV and ADC values in staging of primary uterine cervical cancer (2021) Steiner Aida, Narva Sara, Rinta-Kiikka Irina, Hietanen Sakari, Hynninen Johanna, Virtanen Johanna
- FUNGI: Fusion Gene Integration Toolset (2021) Cervera Alejandra, Rausio Heidi, Kähkönen Tiia, Andersson Noora, Partel Gabriele, Rantanen Ville, Paciello Giulia, Ficarra Elisa, Hynninen Johanna, Hietanen Sakari, Carpén Olli, Lehtonen Rainer, Hautaniemi Sampsa, Huhtinen Kaisa
- Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy (2021) Iyer Sonia, Zhang Shuang, Yucel Simge, Horn Heiko, Smith Sean G, Reinhardt Ferenc, Hoefsmit Esmee, Assatova Bimarzhan, Casado Julia, Meinsohn Marie-Charlotte, Barrasa M Inmaculada, Bell George W, Perez-Villatoro Fernando, Huhtinen Kaisa, Hynninen Johanna, Oikkonen Jaana, Galhenage Pamoda M, Pathania Shailja, Hammond Paula T, Neel Benjamin G, Färkkilä Anniina, Pépin David, Weinberg Robert A.
- Imaging of Tumor Hypoxia With F-18-EF5 PET/MRI in Cervical Cancer (2021)
- Clinical Nuclear Medicine
Narva Sara I., Seppänen Marko P., Raiko Juho R. H., Forsback Sarita J., Orte Katri J., Virtanen Johanna M., Hynninen Johanna, Hietanen Sakari
