Kari Auranen
Ph.D. (biometry, Helsinki University, 1999)
Department of Mathematics and Statistics kajuaur@utu.fi +358 29 450 4320 +358 50 350 6920 Vesilinnantie 5 Turku |
statistical analysis of cohort studies; evaluation of the effects of vaccination and infection mitigation; mathematical models of infection transmission
statistical analysis of infectious disease data; evaluation of population-level effects of vaccination; endpoints in vaccine trials.
I am currently a Professor of Statistics at the Department of Mathematics and Statistics and the Department of Clinical Medicine of the University of Turku (Finland). Before moving to Turku, I worked for almost 20 years on vaccination-related research questions at the Finnish Institute for Health and Welfare.
My own research interests include statistical modelling and analysis of infectious disease data, estimation of vaccine efficacy from trial and field data, dynamics of pneumococcal carriage and its relation to disease, and the effects of vaccination on the epidemiology of the pneumococcus. I have a special interest in Bayesian analysis of incompletely observed infectious disease data and Markov chain Monte Carlo methods applied to deal with the problem. My recent publications in the field of infectious disease data include a survey study of the intensity of social contacts and an analysis of the effectiveness of case isolation and quarantine during the early phase of the SARS-CoV-2 pandemic in Finland. Through my students, I have recently become involved in the analysis of causal mediation in cohort and microbiome studies.
My teaching revolves around various topics related to biostatistics, with emphasis on real-life data analysis and statistical modelling. My recent lecture courses include "Survival analysis", "Design of experiments" and "Statistical methods in epidemiology".
- COVID-19-tutkimuskatsaus 8/2020 (2020) Vapalahti, Olli; Sironen, Tarja; Pimenoff, Ville; Auranen, Kari; Leino, Tuija; Karvonen, Sakari; Toivanen, Otto; Ylöstalo, Hanna; Vainikainen, Mari-Pauliina; Mäkinen, Saku; Arponen, Anni; Heinikoski, Saila; Limnéll, Jarno; Salo, Ahti
- Effectiveness of 10-valent pneumococcal conjugate vaccine estimated with three parallel study designs among vaccine-eligible children in Finland (2020)
- Vaccine
- Effectiveness of 2 Influenza Vaccines in Nationwide Cohorts of Finnish 2-Year-Old Children in the Seasons 2015-2016 Through 2017-2018 (2020)
- Clinical Infectious Diseases
- Impact and effectiveness of a conjugate vaccine against invasive pneumococcal disease in Finland-a modelling approach (2020)
- Human Vaccines and Immunotherapeutics
- Koronaepidemian mallinnuksen lähtökohdat, tavoitteet ja ongelmat (2020)
- Duodecim
- Capturing multiple-type interactions into practical predictors of type replacement following human papillomavirus vaccination (2019)
- Philosophical Transactions B: Biological Sciences
- Effectiveness of the ten-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10) against all respiratory tract infections in children under two years of age (2019)
- Vaccine
- Fast approximate computation of cervical cancer screening outcomes by a deterministic multiple-type HPV progression model (2019)
- Mathematical Biosciences
- Changing molecular epidemiology of methicillin-resistant Staphylococcus aureus in Southwest Finland, 2007 - 2016 (2018) Jenna Junnila, Tiina Hirvioja, Kaisu Rantakokko-Jalava, Kari Auranen, Esa Rintala, Laura Lindholm, Jaakko Silvola, Harri Marttila, Anu Harttio-Nohteri, Kirsi Gröndahl-Yli-Hannuksela, Jaana Vuopio
- F-18-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancer (2018)
- European Journal of Nuclear Medicine and Molecular Imaging
- Long-term impact of 10-valent pneumococcal conjugate vaccination on invasive pneumococcal disease among children in Finland (2018)
- Vaccine
- Surveillance of Circulating Bordetella pertussis Strains in Europe during 1998 to 2015 (2018)
- Journal of Clinical Microbiology
- Acquisition and Transmission of Streptococcus pneumoniae Are Facilitated during Rhinovirus Infection in Families with Children (2017)
- American Journal of Respiratory and Critical Care Medicine
- Epidemiology of hepatitis B infection in Finland: Implications for immunisation policy (2017)
- Vaccine
- Obesity, Underweight, and Smoking are Associated with Worse Cardiorespiratory Fitness in Finnish Healthy Young Men: a Population-Based Study (2017)
- Frontiers in Public Health
- Simulations for designing and interpreting intervention trials in infectious diseases (2017)
- BMC Medicine
- Sustained reduction in vaccine-type invasive pneumococcal disease despite waning effects of a catch-up campaign in Kilifi, Kenya: A mathematical model based on pre-vaccination data (2017)
- Vaccine
- New Pneumococcal Carriage Acquired in Association with Acute Respiratory Infection Is Prone to Cause Otitis Media (2016)
- PLoS ONE
- Revealing the True Incidence of Pandemic A (H1N1)pdm09 Influenza in Finland during the First Two Seasons - An Analysis Based on a Dynamic Transmission Model (2016)
- PLoS ONE
- Optimal observation times for multi-state Markov models - applications to pneumococcal colonisation studies (2015)
- Journal of the Royal Statistical Society: Series C