Laura Airas
Professor of Neuroimmunology, MD, PhD
laura.airas@utu.fi Itäinen Pitkäkatu 4 Turku ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-9751-5881 |
Neurology; Neuroimmunology; Multiple sclerosis; PET-imaging; MRI; Drug development
Multiple sclerosis research, @multiplesclerosisresearchfinland, Neuroinflammation research, INFLAMES Flagship
Laura Airas is an internationally recognized expert in multiple sclerosis (MS) and has served as Professor of Neuroimmunology at the University of Turku since 2017. She also practices clinically as a neurologist at Turku University Hospital, specializing in the care of MS patients.
Professor Airas earned her MD from the University of Turku in 1991 and completed her PhD in immunology and cell biology under Professor Sirpa Jalkanen. Her dissertation was recognized with a special distinction from the University of Turku. She became a specialist in neurology in 2001 and was appointed Associate Professor (docent) in 2007.
Her international experience includes serving as a Visiting Professor at Yale University in 2016–2017. In 2015, she was awarded the prestigious Grant for Multiple Sclerosis Innovation (GMSI).
Professor Airas is a respected member of the international scientific community. She serves as a reviewer for major neurology and neuroimmunology journals and funding agencies, and is a frequent invited speaker at national and international scientific events.
Professor Airas leads a translational and patient-centered research group focusing on the pathophysiology of progressive MS and the development of novel therapeutic strategies. Her research integrates cutting-edge imaging techniques (PET and MRI), biomarker discovery, and genetic analysis to investigate the role of glial cells in brain neurodegeneration.
Her multidisciplinary group of about 20 members includes physicians, biomedical scientists, biosiatisticians, and students. They collaborate widely with national and international partners in PET imaging, immunology, drug development, and neuroscience.
The research is funded by:
- Research Council of Finland
- State Research Funding (VTR)
- Jane and Aatos Erkko Foundation
- U.S.-based organizations including the U.S. Department of Defense, National MS Society, and the Progressive MS Alliance
The group is a member of the InFLAMES Flagship at the University of Turku, where Professor Airas also serves on the leadership team.
In addition to her academic work, Professor Airas has been the Principal Investigator in numerous international multicenter clinical trials. She currently leads two investigator-initiated trials targeting microglial activation to slow down progression of MS.
Professor Laura Airas is actively engaged in teaching at the University of Turku. She lectures in neurology and neuroimmunology for students in the medical and biomedical degree programmes and trains specialist physicians in neurology.
Her teaching approach emphasizes patient-centeredness, integration of clinical care and research, and the application of up-to-date scientific knowledge. She brings insights from the latest breakthroughs in neuroimmunology and clinical trial methodology directly into the classroom.
Professor Airas also supervises PhD candidates and has served as the primary supervisor for several completed doctoral theses. In addition, she contributes to postgraduate education programmes for neurology specialists and neuroscience professionals. She is a sought-after lecturer at both national and international medical education events.
- Whole Brain Adiabatic T-1rho and Relaxation Along a Fictitious Field Imaging in Healthy Volunteers and Patients With Multiple Sclerosis: Initial Findings (2021)
- Journal of Magnetic Resonance Imaging
(A1 Refereed original research article in a scientific journal) - Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis (2020)
- Brain
(A1 Refereed original research article in a scientific journal) - Decreased Availability of Adenosine 2A Receptors in the Caudate in Patients with Early Stage Parkinson’s Disease (2020)
- Movement Disorders
(Other publication) - Drug reaction with eosinophilia and systemic symptoms after ocrelizumab therapy (2020)
- Multiple Sclerosis and Related Disorders
(B1 Non-refereed article in a scientific journal) - Effect of Dopaminergic Medication on Adenosine 2A Receptor Availability in Patients with Parkinson’s Disease (2020) Imran Waggan, Jouni Tuisku, Markus Matilainen, Semi Helin, Riitta Parkkola, Eero Rissanen, Juha Rinne, Laura Airas,
(Other publication) - Exposure to natalizumab during pregnancy and lactation is safe - No (2020)
- Multiple Sclerosis
(B1 Non-refereed article in a scientific journal) - Frequency and etiology of acute transverse myelitis in Southern Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging (2020)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP) (2020)
- Journal of Neurology, Neurosurgery and Psychiatry
(A1 Refereed original research article in a scientific journal) - Mikrogliasolut - aivojen puhdistajat ja puolustajat (2020)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity (2020)
- Multiple Sclerosis
(A1 Refereed original research article in a scientific journal) - Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation (2019)
- EJNMMI Research
(A1 Refereed original research article in a scientific journal) - Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C-11]PBR28 HRRT PET study (2019)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats (2019)
- Journal of Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Natalizumab treatment reduces microglial activation in the white matter of the MS brain (2019)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Progressive dopaminergic defect in a patient with primary progressive multiple sclerosis (2019)
- Multiple Sclerosis and Related Disorders
(B1 Non-refereed article in a scientific journal) - Rituksimabi MS-taudin hoidossa (2019)
- Duodecim
(A1 Refereed original research article in a scientific journal) - Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis (2018)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Evaluation of microglial activation in multiple sclerosis patients using positron emission tomography (2018)
- Frontiers in Neurology
(A2 Refereed review article in a scientific journal )