Laura Airas
Professor of Neuroimmunology, MD, PhD
laura.airas@utu.fi Itäinen Pitkäkatu 4 Turku ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-9751-5881 |
Neurology; Neuroimmunology; Multiple sclerosis; PET-imaging; MRI
Multiple sclerosis research, @multiplesclerosisresearchfinland, Neuroinflammation research, INFLAMES Flagship
Professor Laura Airas obtained her medical degree at the University of Turku, in Turku, Finland. After finishing her PhD on immunology and cell biology, she specialized in neurology, obtaining a neurology consultant status in 2001 and a docentship in neurology in 2007. She founded her own research group in 2002, studying the immunology of pregnancy in MS. Today she serves as a professor of Neuroimmunology at Turku University. She leads a research group whose main aim is to elucidate the pathological mechanisms of progressive MS by using a multi-modal approach including PET-imaging, advanced MRI imaging, and soluble biomarker analysis. Laura Airas is an experienced clinician, and also well connected with scientists of different backgrounds (PET, metabolomics, immunology) and with excellent track records. She spends half of her professional time as a clinical neurologist, consulting for MS-patients at Turku University hospital, and also actively participates in randomised clinical trials for MS. Laura Airas has authored over 130 peer-reviewed articles in international journals. Funding for the group comes from the Finnish Academy, foundations and industry. In 2015 she received an international Grant for Multiple Sclerosis Innovation (GMSI) award, and in 2020 she received an international Progressive Multiple Sclerosis Alliance award. In 2016-2017 she spent the academic year as a visiting professor at Yale University, and was appointed an adjunct professor at Yale school of medicine in 2019.
The major goal of research in Airas group is to understand the pathobiology of multiple sclerosis using noninvasive or minimally invasive imaging methods – particularly MRI and PET. The group develops and performs experiments with new MRI techniques and new PET ligands on state-of-the-art imaging equipment housed in the Turku PET Center, to elucidate the biological underpinnings of imaging abnormalities. This will help understand how such abnormalities relate to clinical disability. Corollary goals of the research are to adapt new imaging and soluble biomarker techniques as biologically (and hopefully clinically) relevant outcome measures in both clinical trials and routine patient care, and to apply them to other inflammatory diseases of the central nervous system.
As a Professor of Neuroimmunology Airas is responsible for neuroimmunological education at the Medical school of the University of Turku. Currently she has under supervision 10 PhD, 4 master’s thesis and 2 extended studies medical students. She participates regularly in domestic and international scientific congresses as a presenter and organizer.
- Clinical Relevance of Brain Volume Measures in Multiple Sclerosis (2014)
- CNS Drugs
(A2 Refereed review article in a scientific journal ) - Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180 (2014)
- Journal of Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - In Vivo Detection of Diffuse Inflammation in Secondary Progressive Multiple Sclerosis Using PET Imaging and the Radioligand 11C-PK11195 (2014)
- Journal of Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - Labour-associated increase in C-reactive protein concentration is not predictive of postpartum relapse activity among mothers with multiple sclerosis. (2014)
- Multiple Sclerosis
(B1 Non-refereed article in a scientific journal) - Specific aspects of modern life for people with multiple sclerosis: considerations for the practitioner (2014)
- Therapeutic Advances in Neurological Disorders
(A2 Refereed review article in a scientific journal ) - Adenosine A2A receptors in secondary progressive multiple sclerosis: a [C-11]TMSX brain PET study (2013)
- Journal of Cerebral Blood Flow and Metabolism
(A1 Refereed original research article in a scientific journal) - Alteration of prolyl oligopeptidase and activated alpha-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome (2013)
- Biochemical Pharmacology
(A1 Refereed original research article in a scientific journal) - Increased thyroid autoimmunity among women with multiple sclerosis in the postpartum setting (2013)
- Multiple Sclerosis
(A1 Refereed original research article in a scientific journal) - Multippeliskleroosi ja raskaus (2013)
- Duodecim
(A2 Refereed review article in a scientific journal ) - A comparative study of two PET radioligands for the imaging of neuroinflammation in an animal model of multiple sclerosis (2012)
- Journal of Neuroimmunology
(Other publication) - Impact of Fingolimod Therapy on Magnetic Resonance Imaging Outcomes in Patients With Multiple Sclerosis (2012)
- Archives of Neurology -Chigago-
(A1 Refereed original research article in a scientific journal) - Pregnancy and multiple sclerosis (2012) Airas Laura, Kaaja Risto
(A1 Refereed original research article in a scientific journal) - Janus head: The dual role of HLA-G in CNS immunity (2011)
- Cellular and Molecular Life Sciences
(A1 Refereed original research article in a scientific journal) - A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis (2010)
- New England Journal of Medicine
(A1 Refereed original research article in a scientific journal) - Breast-feeding, postpartum and prepregnancy disease activity in multiple sclerosis (2010)
- Neurology
(A1 Refereed original research article in a scientific journal) - Carbon monoxide poisoning-induced nigrostriatal dopaminergic dysfunction detected using positron emission tomography (PET) (2010)
- NeuroToxicology
(A1 Refereed original research article in a scientific journal) - Central nervous system immune reconstitution inflammatory syndrome (IRIS) after hematopoietic SCT (2010)
- Bone Marrow Transplantation
(A1 Refereed original research article in a scientific journal) - Is the modulatory effect of pregnancy in multiple sclerosis associated with changes in blood apoptotic molecules? (2010)
- Acta Neurologica Scandinavica
(A1 Refereed original research article in a scientific journal) - Kuinka arvioida puutumisoiretta? (2010)
- Lääkärilehti
(A1 Refereed original research article in a scientific journal) - Phase II study of oral fingolimod (FTY720) in multiple sclerosis: 3-year results (2010)
- Multiple Sclerosis
(A1 Refereed original research article in a scientific journal)