Laura Airas
Professor of Neuroimmunology, MD, PhD
laura.airas@utu.fi Itäinen Pitkäkatu 4 Turku ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-9751-5881(external) |
Neurology; Neuroimmunology; Multiple sclerosis; PET-imaging; MRI; Drug development
Multiple sclerosis research, @multiplesclerosisresearchfinland, Neuroinflammation research, INFLAMES Flagship
Laura Airas is an internationally recognized expert in multiple sclerosis (MS) and has served as Professor of Neuroimmunology at the University of Turku since 2017. She also practices clinically as a neurologist at Turku University Hospital, specializing in the care of MS patients.
Professor Airas earned her MD from the University of Turku in 1991 and completed her PhD in immunology and cell biology under Professor Sirpa Jalkanen. Her dissertation was recognized with a special distinction from the University of Turku. She became a specialist in neurology in 2001 and was appointed Associate Professor (docent) in 2007.
Her international experience includes serving as a Visiting Professor at Yale University in 2016–2017. In 2015, she was awarded the prestigious Grant for Multiple Sclerosis Innovation (GMSI).
Professor Airas is a respected member of the international scientific community. She serves as a reviewer for major neurology and neuroimmunology journals and funding agencies, and is a frequent invited speaker at national and international scientific events.
Professor Airas leads a translational and patient-centered research group focusing on the pathophysiology of progressive MS and the development of novel therapeutic strategies. Her research integrates cutting-edge imaging techniques (PET and MRI), biomarker discovery, and genetic analysis to investigate the role of glial cells in brain neurodegeneration.
Her multidisciplinary group of about 20 members includes physicians, biomedical scientists, biosiatisticians, and students. They collaborate widely with national and international partners in PET imaging, immunology, drug development, and neuroscience.
The research is funded by:
- Research Council of Finland
- State Research Funding (VTR)
- Jane and Aatos Erkko Foundation
- U.S.-based organizations including the U.S. Department of Defense, National MS Society, and the Progressive MS Alliance
The group is a member of the InFLAMES Flagship at the University of Turku, where Professor Airas also serves on the leadership team.
In addition to her academic work, Professor Airas has been the Principal Investigator in numerous international multicenter clinical trials. She currently leads two investigator-initiated trials targeting microglial activation to slow down progression of MS.
Professor Laura Airas is actively engaged in teaching at the University of Turku. She lectures in neurology and neuroimmunology for students in the medical and biomedical degree programmes and trains specialist physicians in neurology.
Her teaching approach emphasizes patient-centeredness, integration of clinical care and research, and the application of up-to-date scientific knowledge. She brings insights from the latest breakthroughs in neuroimmunology and clinical trial methodology directly into the classroom.
Professor Airas also supervises PhD candidates and has served as the primary supervisor for several completed doctoral theses. In addition, she contributes to postgraduate education programmes for neurology specialists and neuroscience professionals. She is a sought-after lecturer at both national and international medical education events.
- Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP) (2020)
- Journal of Neurology, Neurosurgery and Psychiatry
(A1 Refereed original research article in a scientific journal) - Mikrogliasolut - aivojen puhdistajat ja puolustajat (2020)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity (2020)
- Multiple Sclerosis
(A1 Refereed original research article in a scientific journal) - Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation (2019)
- EJNMMI Research
(A1 Refereed original research article in a scientific journal) - Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C-11]PBR28 HRRT PET study (2019)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats (2019)
- Journal of Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Natalizumab treatment reduces microglial activation in the white matter of the MS brain (2019)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Progressive dopaminergic defect in a patient with primary progressive multiple sclerosis (2019)
- Multiple Sclerosis and Related Disorders
(B1 Non-refereed article in a scientific journal) - Rituksimabi MS-taudin hoidossa (2019)
- Duodecim
(A1 Refereed original research article in a scientific journal) - Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis (2018)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Evaluation of microglial activation in multiple sclerosis patients using positron emission tomography (2018)
- Frontiers in Neurology
(A2 Refereed review article in a scientific journal ) - Hemophagocytic lymphohistiocytosis in 2 patients with multiple sclerosis treated with alemtuzumab (2018)
- Neurology
(A1 Refereed original research article in a scientific journal) - Humoral response to John Cunningham virus during pregnancy in multiple sclerosis (2018)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Microglial activation, white matter tract damage, and disability in MS (2018)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Monoklonaaliset vasta-aineet MS-taudin hoidossa (2018)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Positron emission tomography imaging in evaluation of MS pathology in vivo (2018)
- Multiple Sclerosis
(A2 Refereed review article in a scientific journal ) - Severe neutropenia after rituximab-treatment of multiple sclerosis (2018)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Vascular adhesion protein-1 is actively involved in the development of inflammatory lesions in rat models of multiple sclerosis (2018)
- Journal of Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Botulinum toxin alleviates dysphagia of patients with inclusion body myositis (2017)
- Journal of the Neurological Sciences
(A1 Refereed original research article in a scientific journal)