Laura Airas
Professor of Neuroimmunology, MD, PhD
laura.airas@utu.fi Itäinen Pitkäkatu 4 Turku ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-9751-5881 |
Neurology; Neuroimmunology; Multiple sclerosis; PET-imaging; MRI
Multiple sclerosis research, @multiplesclerosisresearchfinland, Neuroinflammation research, INFLAMES Flagship
Professor Laura Airas obtained her medical degree at the University of Turku, in Turku, Finland. After finishing her PhD on immunology and cell biology, she specialized in neurology, obtaining a neurology consultant status in 2001 and a docentship in neurology in 2007. She founded her own research group in 2002, studying the immunology of pregnancy in MS. Today she serves as a professor of Neuroimmunology at Turku University. She leads a research group whose main aim is to elucidate the pathological mechanisms of progressive MS by using a multi-modal approach including PET-imaging, advanced MRI imaging, and soluble biomarker analysis. Laura Airas is an experienced clinician, and also well connected with scientists of different backgrounds (PET, metabolomics, immunology) and with excellent track records. She spends half of her professional time as a clinical neurologist, consulting for MS-patients at Turku University hospital, and also actively participates in randomised clinical trials for MS. Laura Airas has authored over 130 peer-reviewed articles in international journals. Funding for the group comes from the Finnish Academy, foundations and industry. In 2015 she received an international Grant for Multiple Sclerosis Innovation (GMSI) award, and in 2020 she received an international Progressive Multiple Sclerosis Alliance award. In 2016-2017 she spent the academic year as a visiting professor at Yale University, and was appointed an adjunct professor at Yale school of medicine in 2019.
The major goal of research in Airas group is to understand the pathobiology of multiple sclerosis using noninvasive or minimally invasive imaging methods – particularly MRI and PET. The group develops and performs experiments with new MRI techniques and new PET ligands on state-of-the-art imaging equipment housed in the Turku PET Center, to elucidate the biological underpinnings of imaging abnormalities. This will help understand how such abnormalities relate to clinical disability. Corollary goals of the research are to adapt new imaging and soluble biomarker techniques as biologically (and hopefully clinically) relevant outcome measures in both clinical trials and routine patient care, and to apply them to other inflammatory diseases of the central nervous system.
As a Professor of Neuroimmunology Airas is responsible for neuroimmunological education at the Medical school of the University of Turku. Currently she has under supervision 10 PhD, 4 master’s thesis and 2 extended studies medical students. She participates regularly in domestic and international scientific congresses as a presenter and organizer.
- High serum neurofilament associates with diffuse white matter damage in MS (2021)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Increased serum glial fibrillary acidic protein associates with microstructural white matter damage in multiple sclerosis: GFAP and DTI (2021)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - MS-tauti (2021) Kliininen neuropsykiatria Hämäläinen Päivi, Smith Emma, Airas Laura
(D2 Article in a professional compilation book) - Neurosarkoidoosin uudistunut diagnostiikka ja tehostunut hoito (2021)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Oral Doxycycline Compared to Intravenous Ceftriaxone in the Treatment of Lyme Neuroborreliosis: A Multicenter, Equivalence, Randomized, Open-label Trial (2021)
- Clinical Infectious Diseases
(A1 Refereed original research article in a scientific journal) - Positron emission tomography in multiple sclerosis - straight to the target (2021)
- Nature Reviews Neurology
(A2 Refereed review article in a scientific journal ) - Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis (2021)
- Frontiers in Immunology
(A1 Refereed original research article in a scientific journal) - Synaptic Loss in Multiple Sclerosis: A Systematic Review of Human Post-mortem Studies (2021)
- Frontiers in Neurology
(A2 Refereed review article in a scientific journal ) - Update on the management of multiple sclerosis during the COVID-19 pandemic and post pandemic: An international consensus statement (2021)
- Journal of Neuroimmunology
(A2 Refereed review article in a scientific journal ) - Whole Brain Adiabatic T-1rho and Relaxation Along a Fictitious Field Imaging in Healthy Volunteers and Patients With Multiple Sclerosis: Initial Findings (2021)
- Journal of Magnetic Resonance Imaging
(A1 Refereed original research article in a scientific journal) - Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis (2020)
- Brain
(A1 Refereed original research article in a scientific journal) - Decreased Availability of Adenosine 2A Receptors in the Caudate in Patients with Early Stage Parkinson’s Disease (2020)
- Movement Disorders
(Other publication) - Drug reaction with eosinophilia and systemic symptoms after ocrelizumab therapy (2020)
- Multiple Sclerosis and Related Disorders
(B1 Non-refereed article in a scientific journal) - Effect of Dopaminergic Medication on Adenosine 2A Receptor Availability in Patients with Parkinson’s Disease (2020) Imran Waggan, Jouni Tuisku, Markus Matilainen, Semi Helin, Riitta Parkkola, Eero Rissanen, Juha Rinne, Laura Airas,
(Other publication) - Exposure to natalizumab during pregnancy and lactation is safe - No (2020)
- Multiple Sclerosis
(B1 Non-refereed article in a scientific journal) - Frequency and etiology of acute transverse myelitis in Southern Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal) - Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging (2020)
- Neurology, Neuroimmunology and Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP) (2020)
- Journal of Neurology, Neurosurgery and Psychiatry
(A1 Refereed original research article in a scientific journal) - Mikrogliasolut - aivojen puhdistajat ja puolustajat (2020)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland (2020)
- Multiple Sclerosis and Related Disorders
(A1 Refereed original research article in a scientific journal)