Laura Airas
Professor of Neuroimmunology, MD, PhD
laura.airas@utu.fi +358 29 450 4746 +358 50 472 8599 Itäinen Pitkäkatu 4 Turku ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-9751-5881 |
Neurology; Neuroimmunology; Multiple sclerosis; PET-imaging; MRI
Professor Laura Airas obtained her medical degree at the University of Turku, in Turku, Finland. After finishing her PhD on immunology and cell biology, she specialized in neurology, obtaining a neurology consultant status in 2001 and a docentship in neurology in 2007. She founded her own research group in 2002, studying the immunology of pregnancy in MS. Today she serves as a professor of Neuroimmunology at Turku University. She leads a research group whose main aim is to elucidate the pathological mechanisms of progressive MS by using a multi-modal approach including PET-imaging, advanced MRI imaging, and soluble biomarker analysis. Laura Airas is an experienced clinician, and also well connected with scientists of different backgrounds (PET, metabolomics, immunology) and with excellent track records. She spends half of her professional time as a clinical neurologist, consulting for MS-patients at Turku University hospital, and also actively participates in randomised clinical trials for MS. Laura Airas has authored over 130 peer-reviewed articles in international journals. Funding for the group comes from the Finnish Academy, foundations and industry. In 2015 she received an international Grant for Multiple Sclerosis Innovation (GMSI) award, and in 2020 she received an international Progressive Multiple Sclerosis Alliance award. In 2016-2017 she spent the academic year as a visiting professor at Yale University, and was appointed an adjunct professor at Yale school of medicine in 2019.
The major goal of research in Airas group is to understand the pathobiology of multiple sclerosis using noninvasive or minimally invasive imaging methods – particularly MRI and PET. The group develops and performs experiments with new MRI techniques and new PET ligands on state-of-the-art imaging equipment housed in the Turku PET Center, to elucidate the biological underpinnings of imaging abnormalities. This will help understand how such abnormalities relate to clinical disability. Corollary goals of the research are to adapt new imaging and soluble biomarker techniques as biologically (and hopefully clinically) relevant outcome measures in both clinical trials and routine patient care, and to apply them to other inflammatory diseases of the central nervous system.
As a Professor of Neuroimmunology Airas is responsible for neuroimmunological education at the Medical school of the University of Turku. Currently she has under supervision 10 PhD, 4 master’s thesis and 2 extended studies medical students. She participates regularly in domestic and international scientific congresses as a presenter and organizer.
- Adenosine A2A receptor availability in cerebral gray and white matter of patients with Parkinson's disease (2023)
- Parkinsonism and Related Disorders
(Refereed journal article or data article (A1)) - Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson’s disease (2023)
- Journal of Neurology
(Refereed journal article or data article (A1)) - Association of serum neurofilament light with microglial activation in multiple sclerosis (2023)
- Journal of Neurology, Neurosurgery and Psychiatry
(Refereed journal article or data article (A1)) - Diagnosis and treatment of progressive multiple sclerosis: A position paper (2023)
- European Journal of Neurology
(Refereed journal article or data article (A1)) - Early prognosticators of later TSPO-PET-measurable microglial activation in multiple sclerosis (2023)
- Multiple Sclerosis and Related Disorders
(Refereed journal article or data article (A1)) - Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis (2023)
- European Journal of Neurology
(Refereed journal article or data article (A1)) - PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report (2023)
- Journal of Neurology
(Refereed journal article or data article (A1)) - TSPO-Detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis (2023)
- Neurology, Neuroimmunology and Neuroinflammation
(Refereed journal article or data article (A1)) - Anti-SARS-CoV-2 vaccination in people with multiple sclerosis: Lessons learnt a year in (2022)
- Frontiers in Immunology
(Refereed review article in scientific journal (A2)) - Association between microglial activation and serum kynurenine pathway metabolites in multiple sclerosis patients (2022)
- Multiple Sclerosis and Related Disorders
(Refereed journal article or data article (A1)) - CANVAS - tasapainovaikeuksien ja kroonisen yskän mahdollinen aiheuttaja (2022)
- Duodecim
(Article in trade journal or blog post (D1)) - Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation (2022)
- EJNMMI Research
(Refereed journal article or data article (A1)) - Epstein-Barrin virus MS-taudin ajurina (2022)
- Duodecim
(Article in trade journal or blog post (D1)) - Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient (2022)
- Stem Cell Research
(Refereed journal article or data article (A1)) - Innate Immune Cell-Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis (2022)
- Neurology, Neuroimmunology and Neuroinflammation
(Refereed journal article or data article (A1)) - Microglia in multiple sclerosis - Pathogenesis and imaging (2022)
- Current Opinion in Neurology
(Refereed review article in scientific journal (A2)) - MS-taudin varhainen ja tehokas hoito kannattaa (2022)
- Erikoislääkäri
(Article in trade journal or blog post (D1)) - Phenotyping of multiple sclerosis lesions according to innate immune cell activation using TSPO-PET (2022)
- Brain Communications
(Refereed journal article or data article (A1)) - Raskauden vaikutukset soluvälitteisiin autoimmuunitauteihin - erityisesti MS-tautiin (2022)
- Duodecim
(Refereed review article in scientific journal (A2)) - Smouldering multiple sclerosis: the 'real MS' (2022)
- Therapeutic Advances in Neurological Disorders
(Refereed review article in scientific journal (A2))