Maria Sundvall
MD PhD; Specialist Physician in Clinical Oncology
mahesu@utu.fi Kiinamyllynkatu 10 Turku |
Areas of expertise
clinical oncology; breast and prostate cancer; targeted cancer therapeutics; cancer biology; cell signaling; posttranslational modifications; dna repair pathways
clinical oncology; breast and prostate cancer; targeted cancer therapeutics; cancer biology; cell signaling; posttranslational modifications; dna repair pathways
Biography
Maria Sundvall received her MD degree from the University of Turku in 2003, and defended her PhD thesis at the Department of Medical Biochemistry and Genetics, University of Turku, in 2007. From 2011 she worked nearly 4 years as a postdoctoral fellow in the laboratory of Prof. Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA. After returning to Finland in 2015 she established her own research group at the University of Turku. Dr. Sundvall received a specialist physician degree in clinical oncology in 2018. Since 2018 Dr. Sundvall has worked as a part-time clinical lecturer at the Institute of Biomedicine, a part-time Academy of Finland clinical researcher and a part-time specialist physician in clinical oncology at Turku University Hospital.
Maria Sundvall received her MD degree from the University of Turku in 2003, and defended her PhD thesis at the Department of Medical Biochemistry and Genetics, University of Turku, in 2007. From 2011 she worked nearly 4 years as a postdoctoral fellow in the laboratory of Prof. Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA. After returning to Finland in 2015 she established her own research group at the University of Turku. Dr. Sundvall received a specialist physician degree in clinical oncology in 2018. Since 2018 Dr. Sundvall has worked as a part-time clinical lecturer at the Institute of Biomedicine, a part-time Academy of Finland clinical researcher and a part-time specialist physician in clinical oncology at Turku University Hospital.
Research
Dr. Sundvall has 20 years of experience in studying molecular mechanisms of cancer. Currently she is a principal investigator at University of Turku, and her group is focusing on investigating the role fo DNA repair pathways in prostate cancer. Links:
https://www.utu.fi/en/university/faculty-of-medicine/institute-of-biomedicine/research/cancer-research
Teaching
Dr. Sundvall has several years of experience in teaching medical students as a clinical lecturer and a university teacher in the fields of medical biochemistry, molecular medicine and cancer during the last 15 years.
Dr. Sundvall has several years of experience in teaching medical students as a clinical lecturer and a university teacher in the fields of medical biochemistry, molecular medicine and cancer during the last 15 years.
Publications
- High comorbidity and tumor proliferation predict survival of localized breast cancer patients after curative surgery: A retrospective analysis of real-world data in Finland (2025)
- Surgical Oncology
(A1 Refereed original research article in a scientific journal) - Phage Biosensor for the Classification of Metastatic Urological Cancers from Urine (2024)
- Life
(A1 Refereed original research article in a scientific journal) - Syövän kohdennettujen lääkehoitojen tulevaisuus (2024)
- Duodecim
(A2 Refereed review article in a scientific journal ) - TIMP-1 is an activator of MHC-I expression in myeloid dendritic cells with implications for tumor immunogenicity (2024)
- Genes and Immunity
(A1 Refereed original research article in a scientific journal) - xCT as a Predictor for Survival in a Population‐Based Cohort of Head and Neck Squamous Cell Carcinoma (2024)
- Cancer Medicine
(A1 Refereed original research article in a scientific journal) - Effect of caldesmon mutations in the development of zebrafish embryos (2023)
- Biochemical and Biophysical Research Communications
(A1 Refereed original research article in a scientific journal) - Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer (2023)
- Oncogenesis
(A1 Refereed original research article in a scientific journal) - Radium-223 dichloride treatment in metastatic castration-resistant prostate cancer in Finland: A real-world evidence multicenter study (2023)
- Cancer Medicine
(A1 Refereed original research article in a scientific journal) - TSPO is a potential independent prognostic factor associated with cellular respiration and p16 in head and neck squamous cell carcinoma (2023)
- Frontiers in Oncology
(A1 Refereed original research article in a scientific journal) - Ex vivo -mallit ja nestebiopsia yksilöllistetyssä syövänhoidossa (2021)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Geeniohjatun syövän hoidon työryhmä hoitopäätösten apuna : Läntisen syöpäkeskuksen kokemus (2021)
- Duodecim
(D1 Article in a professional journal) - More Than Meets the Eye: Scientific Rationale behind Molecular Imaging and Therapeutic Targeting of Prostate-Specific Membrane Antigen (PSMA) in Metastatic Prostate Cancer and Beyond (2021)
- Cancers
(A2 Refereed review article in a scientific journal ) - Therapeutic Potential of Targeting the SUMO Pathway in Cancer (2021)
- Cancers
(A2 Refereed review article in a scientific journal ) - Role of Ubiquitin and SUMO in Intracellular Trafficking (2020)
- Current Issues in Molecular Biology
(A1 Refereed original research article in a scientific journal) - Uusia työkaluja paikallisesti edenneen ja etäpesäkkeisen eturauhassyövän lääkehoitoon (2020)
- Duodecim
(A2 Refereed review article in a scientific journal ) - PARP Inhibitors in Prostate Cancer-the Preclinical Rationale and Current Clinical Development (2019)
- Genes
(A2 Refereed review article in a scientific journal ) - Role of Ubiquitin and SUMO in Intracellular Trafficking (2019) SUMOylation and Ubiquitination: Current and Emerging Concepts Maria Sundvall
(Other publication) - Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin (2018)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - SUMOylation regulates nuclear accumulation and signaling activity of the soluble intracellular domain of the ErbB4 receptor tyrosine kinase (2017)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - ERBB4 Promoter Polymorphism Is Associated with Poor Distant Disease-Free Survival in High-Risk Early Breast Cancer (2014)
- PLoS ONE
(A1 Refereed original research article in a scientific journal)