Antti-Pekka Laine - UTU Tutkimustietojärjestelmä

Antti-Pekka Laine

- Senior Researcher,
Institute of Biomedicine (Faculty of Medicine)
- Project Researcher,
MediCity (Faculty of Medicine)

aplaine@utu.fi

+358 29 450 4386

+358 50 352 0067

Tykistökatu 6

Turku

Publications

1 of 3

CXADR polymorphism rs6517774 modifies islet autoimmunity characteristics and exhibits sex disparity (2023)
- Frontiers in Genetics
Nygård Lucas, Valta Milla, Laine Antti-Pekka, Toppari Jorma, Knip Mikael, Veijola Riitta, Hyöty Heikki, Ilonen Jorma, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)
Associations between deduced first islet specific autoantibody with sex, age at diagnosis and genetic risk factors in young children with type 1 diabetes (2022)
- Pediatric Diabetes
Ilonen Jorma, Laine Antti-Pekka, Kiviniemi Minna, Härkonen Taina, Lempainen Johanna, Knip Mikael
(A1 Refereed original research article in a scientific journal)
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage (2022)
- Diabetologia
Sioofy-Khojine Amir-Babak, Richardson Sarah J., Locke Jonathan M., Oikarinen Sami, Nurminen Noora, Laine Antti-Pekka, Downes Kate, Lempainen Johanna, Todd John A., Veijola Riitta, Ilonen Jorma, Knip Mikael, Morgan Noel G., Hyöty Heikki, Peakman Mark, Eichmann Martin
(A1 Refereed original research article in a scientific journal)
Non-HLA Gene Polymorphisms in the Pathogenesis of Type 1 Diabetes: Phase and Endotype Specific Effects (2022)
- Frontiers in Immunology
Laine Antti-Pekka, Valta Milla, Toppari Jorma, Knip Mikael, Veijola Riitta, Ilonen Jorma, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)
Associations Between IFI44L Gene Variants and Rates of Respiratory Tract Infections During Early Childhood (2021)
- Journal of Infectious Diseases
Lempainen Johanna, Korhonen Laura S, Kantojärvi Katri, Heinonen Santtu, Toivonen Laura, Räty Panu, Ramilo Octavio, Mejias Asuncion, Laine Antti-Pekka, Vuorinen Tytti, Waris Matti, Karlsson Linnea, Karlsson Hasse, Paunio Tiina, Peltola Ville
(A1 Refereed original research article in a scientific journal)
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population (2021)
- Human Immunology
Nygård Lucas, Laine Antti-Pekka, Kiviniemi Minna, Toppari Jorma, Härkönen Taina, Knip Mikael, Veijola Rittta, Lempainen Johanna, Ilonen Jorma
(A1 Refereed original research article in a scientific journal)
HLA-DR-DQ haplotypes and specificity of the initial autoantibody in islet specific autoimmunity (2020)
- Pediatric Diabetes
Mikk Mari-Liis, Pfeiffer Sophie, Kiviniemi Minna, Laine Antti-Pekka, Lempainen Johanna, Härkönen Taina, Toppari Jorma, Veijola Riitta, Knip Mikael, Ilonen Jorma; The Finnish Pediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
Longitudinal Pattern of First-Phase Insulin Response Is Associated With Genetic Variants Outside the Class II HLA Region in Children With Multiple Autoantibodies (2020)
- Diabetes
Maarit K. Koskinen, Mari-Liis Mikk, Antti-Pekka Laine, Johanna Lempainen, Eliisa Löyttyniemi, Paula Vähäsalo, Anne Hekkala, Taina Härkönen, Minna Kiviniemi, Olli Simell, Mikael Knip, Riitta Veijola, Jorma Ilonen, Jorma Toppari
(A1 Refereed original research article in a scientific journal)
Characteristics of Slow Progression to Type 1 Diabetes in Children With Increased HLA-Conferred Disease Risk (2019)
- Journal of Clinical Endocrinology and Metabolism
Siljander H., Ilonen J., Knip M., Pöllänen P., Lempainen J., Laine A., Toppari J., Veijola R.
(A1 Refereed original research article in a scientific journal)
Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity (2018)
- Pediatric Diabetes
Jorma Ilonen, Johanna Lempainen, Anna Hammais, Antti-Pekka Laine, Taina Härkönen, Jorma Toppari, Riitta Veijola, Mikael Knip
(A1 Refereed original research article in a scientific journal)
Characterisation of rapid progressors to type 1 diabetes among children with HLA-conferred disease susceptibility (2017)
- Diabetologia
Pollanen PM, Lempainen J, Laine AP, Toppari J, Veijola R, Vahasalo P, Ilonen J, Siljander H, Knip M
(A1 Refereed original research article in a scientific journal)
HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes (2017)
- PLoS ONE
Parkkola A, Laine AP, Karhunen M, Härkönen T, Ryhänen SJ, Ilonen J, Knip M
(A1 Refereed original research article in a scientific journal)
The association of the HLA-A*24:02, B*39:01 and B*39:06 alleles with type 1 diabetes is restricted to specific HLA-DR/DQ haplotypes in Finns (2017)
- HLA
Mikk ML, Heikkinen T, El-Amir MI, Kiviniemi M, Laine AP, Harkonen T, Veijola R, Toppari J, Knip M, Ilonen J
(A1 Refereed original research article in a scientific journal)
GIMAP GTPase Family Genes: Potential Modifiers in Autoimmune Diabetes, Asthma, and Allergy (2015)
- Journal of Immunology
Heinonen MT, Laine AP, Soderhall C, Gruzieva O, Rautio S, Melen E, Pershagen G, Lahdesmaki HJ, Knip M, Ilonen J, Henttinen TA, Kere J, Lahesmaa R
(A1 Refereed original research article in a scientific journal)
Non-HLA gene effects on the disease process of type 1 diabetes: From HLA susceptibility to overt disease (2015)
- Journal of Autoimmunity
Lempainen J, Laine AP, Hammais A, Toppari J, Simell O, Veijola R, Knip M, Ilonen J
(A1 Refereed original research article in a scientific journal)
Risk genes and autoantibodies in Egyptian children with type 1 diabetes - low frequency of autoantibodies in carriers of the HLA-DRB1*04:05-DQA1*03-DQB1*02 risk haplotype (2015)
- Diabetes/Metabolism Research and Reviews
Mostafa I. El-Amir, Mohamed Ali El-Feky, Antti-Pekka Laine, Taina Härkönen, Omnia El-Badawy, Azza A. Eltayeb, Tarek Taha El-Melegy, Minna Kiviniemi, Mikael Knip, Jorma Ilonen
(A1 Refereed original research article in a scientific journal)
Circulating concentrations of soluble receptor for AGE are associated with age and AGER gene polymorphisms in children with newly diagnosed type 1 diabetes (2014)
- Diabetes Care
Kirsi M. Salonen, Samppa J. Ryhänen, Josephine M. Forbes, Taina Härkönen, Jorma Ilonen, Antti-Pekka Laine, Per-Henrik Groop, Mikael Knip for the Finnish Pediatric Diabetes Registe
(A1 Refereed original research article in a scientific journal)
The HLA-B∗39 allele increases type 1 diabetes risk conferred by HLA-DRB1∗04:04-DQB1∗03:02 and HLA-DRB1∗08-DQB1∗04 class II haplotypes (2014)
- Human Immunology
M.-L. Mikk, M. Kiviniemi, A.-P. Laine, T. Härkönen, R. Veijola, O. Simell, M. Knip, J. Ilonen; and the Finnish Paediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
Associations of polymorphisms in non-HLA loci with autoantibodies at the diagnosis of type 1 diabetes – INS and IKZF4 associate with insulin autoantibodies (2013)
- Pediatric Diabetes
Lempainen J, Härkönen T, Laine AP, Knip M, Ilonen J, The Finnish Pediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
Patterns of beta-Cell Autoantibody Appearance and Genetic Associations During the First Years of Life (2013)
- Diabetes
Ilonen J, Hammais A, Laine AP, Lempainen J, Vaarala O, Veijola R, Simell O, Knip M
(A1 Refereed original research article in a scientific journal)