Born in Moscow, USSR.

Graduated from the Lomonosov Moscow State University.

Post-graduate student in the Institute of
Molecular Biology of USSR Academy of Sciences.

Got a PhD degree accepted by the Higher Attestation Commission
under the USSR Council of Ministers.

At present: Adjunct Professor of Molecular Biology appointed by the University of Turku, Finland

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CyanoPhosphoProteomics: A search for novel signaling and regulatory
pathways in cyanobacteria 

Research of photosynthetic organisms, with
its potential for development of a renewable and CO₂-neutral energy system, has
become increasingly important in the last decade and attracted significant
attention of the society.  Cyanobacteria
are among the most important candidates for the efficient production of targeted chemicals and fuels because they can produce desirable compounds using only sunlight, water and inorganic nutrients.
The present project intends to reveal in cyanobacteria hidden pathways of
regulation and signaling which are based on Ser/Thr and Tyr protein
phosphorylation. The
aim of the research is to investigate cyanobacterial
phosphoproteins in order to i) discover novel protein phosphorylation sites,
ii) study dynamics of protein phosphorylation events in response to various
environmental stimuli, iii) assign links between phosphoproteins and
corresponding kinases, and iv) find out how the phosphorylation signal is
processed and reflected in intracellular changes. In order to stimulate various signaling pathways, cells
will be challenged by environmental stresses (light/darkness, carbon, nitrogen
and other nutrients limitations). Phosphoproteins will be examined using innovative quantitative and targeted
mass spectrometry, molecular biology and genetic engineering methods aiming to
get novel insights into a complicated network of the post-translational
regulation and signaling. Exploration of cyanobacterial phosphoproteomes will
significantly expand our knowledge of fundamental processes occurring in
blue-green alga, such as oxygenic photosynthesis, nitrogen fixation, CO₂
uptake, hydrogen production, cell differentiation, etc., and will lead to novel
technological applications.

Supervising of the PhD studies

Lectures:   

SYST1010, “Systems biology lectures”, three
lectures (“Proteomics I: Proteomes and proteomic approaches. Preparation of
samples for mass spectrometry analysis”; “Proteomics II: Basics in mass
spectrometry of peptides”, and “Proteomics III: Quantitative proteomics and
PTMs” (2014, 2015, 2016, 2017, 2018)

SYST
5044 (KABI 5044), “Introduction to Bioenergetics”, the lecture “Proteomics in
photosynthesis” (2015, 2016, 2017, 2018)

SYST1100,
“ Bioinformatics”, the lecture “"Biological databases" and practical
exercises “Acquaintance with NCBI" (2014, 2015, 2016)