Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Antibody engineering, Bioaffinity assays, in vitro diagnostics
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
- A simple heterogeneous one-step assay for screening estrogenic compounds (2013)
- Biotechnology Letters
- Genetically Encoded Protease Substrate Based on Lanthanide-Binding Peptide for Time-Gated Fluorescence Detection (2013)
- Analytical Chemistry
- Identification of a Novel Bacterial Outer Membrane Interleukin-1B-Binding Protein from Aggregatibacter actinomycetemcomitans (2013)
- PLoS ONE
- Multiresidue Detection of Fluoroquinolones: Specificity Engineering of a Recombinant Antibody with Oligonucleotide-Directed Mutagenesis (2013)
- Journal of Agricultural and Food Chemistry
- Quantitative PCR detection and improved sample preparation of microcystin-producing Anabaena, Microcystis and Planktothrix (2013)
- Ecotoxicology and Environmental Safety
- Two ScFv antibody libraries derived from identical VLVH framework with different binding site designs display distinct binding profiles (2013)
- Protein Engineering, Design and Selection
- High-performance closed-tube PCR based on switchable luminescence probes (2012)
- Analytica Chimica Acta
- Homogenous M13 bacteriophage quantification assay using switchable lanthanide fluorescence probes (2012)
- Biotechniques
- Primer Extension Mutagenesis Powered by Selective Rolling Circle Amplification (2012)
- PLoS ONE
- Cd-specific mutants of mercury-sensing regulatory protein MerR, generated by directed evolution (2011)
- Applied and Environmental Microbiology



