Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Areas of expertise
Antibody engineering, Bioaffinity assays, in vitro diagnostics
Antibody engineering, Bioaffinity assays, in vitro diagnostics
Research
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Teaching
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
Publications
- Aberrantly glycosylated PSMA in urine as a potential marker for prostate cancer (2026)
- Clinica Chimica Acta
(A1 Refereed original research article in a scientific journal) - Development of an Anti-Immunocomplex Antibody and Non-competitive Immunoassay for the Detection of Testosterone (2026)
- Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - Fluorine-18 Radiolabeled Single-Chain Antibody Variable Fragment 1F4 Targets α1-Subunit Gamma-Aminobutyric Acid Type A Receptors in Mice (2026)
- Journal of Medicinal Chemistry
(A1 Refereed original research article in a scientific journal) - Developing and validating anti-ADA2 single-chain antibodies coupled to alkaline phosphatase for diagnosing pleural tuberculosis (2025)
- Frontiers in immunology
(A1 Refereed original research article in a scientific journal) - Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance (2025)
- Signal Transduction and Targeted Therapy
(A1 Refereed original research article in a scientific journal) - High‐Sensitivity Detection of Urinary Extracellular Vesicles With Upconverting Nanoparticle‐Based Lateral Flow Immunoassay (2025)
- Journal of Extracellular Biology
(A1 Refereed original research article in a scientific journal) - Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)
- Journal of Neurology, Neurosurgery and Psychiatry
(A1 Refereed original research article in a scientific journal) - Controlled labelling of tracer antibodies for time-resolved fluorescence-based immunoassays (2024)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Epitope-specific antibody fragments block aggregation of AGelD187N, an aberrant peptide in gelsolin amyloidosis (2024)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells (2024)
- Biomedicine and Pharmacotherapy
(A1 Refereed original research article in a scientific journal) - Increased stable integration efficiency in CHO cells through enhanced nuclear localization of Bxb1 serine integrase (2024)
- BMC Biotechnology
(A1 Refereed original research article in a scientific journal) - Plasma CHI3L1 associates with increased TSPO-PET measurable microglial activation in patients with progressive multiple sclerosis (2024)
- Multiple Sclerosis
(Poster) - Tetraspanin immunoassay for the detection of extracellular vesicles and renal cell carcinoma (2024)
- Nano select
(A1 Refereed original research article in a scientific journal) - Genotyped functional screening of soluble Fab clones enables in-depth analysis of mutation effects (2023)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - ImmunoPET Directed to the Brain: A New Tool for Preclinical and Clinical Neuroscience (2023)
- Biomolecules
(A2 Refereed review article in a scientific journal ) - Isolation and functional analysis of phage-displayed antibody fragments targeting the staphylococcal superantigen-like proteins (2023)
- MicrobiologyOpen
(A1 Refereed original research article in a scientific journal) - Lectins as potential tools for cancer biomarker discovery from extracellular vesicles (2023)
- Biomarker research
(A2 Refereed review article in a scientific journal ) - RECOMBINANT ANTIBODIES AGAINST ANATOXIN: A CYANOBACTERIAL NEUROTOXIN (2023)
- Clinical Chemistry and Laboratory Medicine
(Other publication) - Selection of biophysically favorable antibody variants using a modified Flp-In CHO mammalian display platform (2023)
- Frontiers in Bioengineering and Biotechnology
(A1 Refereed original research article in a scientific journal) - Archaic chaperone-usher pili self-secrete into superelastic zigzag springs (2022)
- Nature
(A1 Refereed original research article in a scientific journal)



