Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Antibody engineering, Bioaffinity assays, in vitro diagnostics
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
- Eph Receptors as Drug Targets: Single-Chain Antibodies and Beyond (2015)
- Current Drug Targets
- Fast conversion of scFv to Fab antibodies using type IIs restriction enzymes (2015)
- Journal of Immunological Methods
- GTP-Specific Fab Fragment-Based GTPase Activity Assay (2015)
- Analytical Chemistry
- Phage display aided improvement of a unique prostate-specific antigen (PSA) antibody unreactive with Lys(145)-Lys(146) internally cleaved forms (2015)
- Journal of Immunological Methods
- Precise construction of oligonucleotide-Fab fragment conjugate for homogeneous immunoassay using HaloTag technology (2015)
- Analytical Biochemistry
- A homogeneous quenching resonance energy transfer assay for H-Ras activation cycle monitoring and inhibitor screening (2014)
- New Biotechnology
- Generation and characterization of a single-chain anti-EphA2 antibody (2014)
- Growth Factors
- Lactobacillus helveticus MIMLh5-specific antibodies for detection of S-layer protein in Grana Padano protected-designation-of-origin cheese (2014)
- Applied and Environmental Microbiology
- Rapid quantification of mcyB copy numbers on dry chemistry PCR chips and predictability of microcystin concentrations in freshwater environments (2014)
- Harmful Algae
- The selection performance of an antibody library displayed on filamentous phage coat proteins p9, p3 and truncated p3 (2014)
- BMC Research Notes



