Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Antibody engineering, Bioaffinity assays, in vitro diagnostics
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
5 of 5
- Primer Extension Mutagenesis Powered by Selective Rolling Circle Amplification (2012)
- PLoS ONE
- Cd-specific mutants of mercury-sensing regulatory protein MerR, generated by directed evolution (2011)
- Applied and Environmental Microbiology
- Directed antibody-engineering techniques and their applications in food immunoassays (2011)
- Trends in Analytical Chemistry
- Engineering of a broad-specificity antibody: Detection of eight fluoroquinolone antibiotics simultaneously (2011)
- Analytical Biochemistry
- Enhanced error-prone RCA mutagenesis by concatemer resolution (2011)
- Plasmid
- Homogeneous detection of avidin based on switchable lanthanide luminescence (2011)
- Analytical Chemistry
- Homogeneous Single-Label Biochemical Ras Activation Assay Using Time-Resolved Luminescence (2011)
- Analytical Chemistry
- Synthetic single-framework antibody library integrated with rapid affinity maturation by V-L shuffling (2011)
- Protein Engineering, Design and Selection
- Luminescence switching by hybridization-directed mixed lanthanide complex formation (2010)
- Analytical Chemistry
- Oligovalent Fab Display on M13 Phage Improved by Directed Evolution (2010)
- Molecular Biotechnology
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