Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Antibody engineering, Bioaffinity assays, in vitro diagnostics
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
4 of 5
- Recombinant antibodies for specific detection of clostridial [Fe-Fe] hydrogenases (2016)
- Scientific Reports
- Role of lectin microarrays in cancer diagnosis (2016)
- ProteomicsHarmful Algae
- Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains of Yersinia for host tissues (2016)
- Molecular MicrobiologyCurrent Drug Targets
- Detection of cyanobacterial sxt genes and paralytic shellfish toxins in freshwater lakes and brackish waters on Åland Islands, FinlandFast conversion of scFv to Fab antibodies using type IIs restriction enzymes (2015)
- Eph Receptors as Drug Targets: Single-Chain Antibodies and Beyond (2015)
- (2015)
- Journal of Immunological MethodsJournal of Immunological Methods
- GTP-Specific Fab Fragment-Based GTPase Activity Assay2015
- Analytical ChemistryAnalytical Biochemistry
- A homogeneous quenching resonance energy transfer assay for H-Ras activation cycle monitoring and inhibitor screening (2015)
- Precise construction of oligonucleotide-Fab fragment conjugate for homogeneous immunoassay using HaloTag technology (2015)
- (2014)
- New Biotechnology
- Generation and characterization of a single-chain anti-EphA2 antibody (2014)
- Growth FactorsApplied and Environmental Microbiology
- Lactobacillus helveticus MIMLh5-specific antibodies for detection of S-layer protein in Grana Padano protected-designation-of-origin cheeseRapid quantification of mcyB copy numbers on dry chemistry PCR chips and predictability of microcystin concentrations in freshwater environments (2014)
- (2014)
- Harmful Algae
- The selection performance of an antibody library displayed on filamentous phage coat proteins p9, p3 and truncated p3 (2014)
- BMC Research Notes
- A simple heterogeneous one-step assay for screening estrogenic compounds (2013)
- Biotechnology Letters
- Genetically Encoded Protease Substrate Based on Lanthanide-Binding Peptide for Time-Gated Fluorescence Detection (2013)
- Analytical Chemistry
- Identification of a Novel Bacterial Outer Membrane Interleukin-1B-Binding Protein from Aggregatibacter actinomycetemcomitans (2013)
- PLoS ONE
- Multiresidue Detection of Fluoroquinolones: Specificity Engineering of a Recombinant Antibody with Oligonucleotide-Directed Mutagenesis (2013)
- Journal of Agricultural and Food Chemistry
- Quantitative PCR detection and improved sample preparation of microcystin-producing Anabaena, Microcystis and Planktothrix (2013)
- Ecotoxicology and Environmental Safety
- Two ScFv antibody libraries derived from identical VLVH framework with different binding site designs display distinct binding profiles (2013)
- Protein Engineering, Design and Selection
UTU Research Portal