Urpo Lamminmäki
PhD
urplammi@utu.fi +358 29 450 4587 +358 50 476 5557 Kiinamyllynkatu 10 Turku |
Antibody engineering, Bioaffinity assays, in vitro diagnostics
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
- Archaic chaperone-usher pili self-secrete into superelastic zigzag springs (2022)
- Nature
- Generation of a Large Repertoire of Monoclonal Antibodies against Dengue Virus NS1 Antigen and the Development of a Novel NS1 Detection Enzyme-Linked Immunosorbent Assay (2022)
- Journal of Immunology
- Integrins are enriched on aberrantly fucosylated tumour‐derived urinary extracellular vesicles (2022)
- Journal of Extracellular Biology
- Isolation and characterization of phage display-derived scFv antibodies against human parechovirus 1 VP0 protein (2022)
- Scientific Reports
- Single-step noncompetitive immunocomplex immunoassay for rapid aflatoxin detection (2022)
- Food Chemistry
- Synonymous Codons and Hydrophobicity Optimization of Post-translational Signal Peptide PelB Increase Phage Display Efficiency of DARPins (2022)
- ACS Synthetic Biology
- Time-resolved fluorescence based direct two-site apoA-I immunoassays and their clinical application in patients with suspected obstructive coronary artery disease (2022)
- Frontiers in Cardiovascular Medicine
- A 15-min non-competitive homogeneous assay for microcystin and nodularin based on time-resolved Förster resonance energy transfer (TR-FRET) (2021)
- Analytical and Bioanalytical Chemistry
- Combinatorial mutagenesis with alternative CDR-L1 and-H2 loop lengths contributes to affinity maturation of antibodies (2021)
- New Biotechnology
- Detection of bladder cancer with aberrantly fucosylated ITGA3 (2021)
- Analytical Biochemistry



