PhD Urpo Lamminmäki - UTU Research Portal

Urpo Lamminmäki
PhD

- ,
InFLAMES Flagship (Faculty of Medicine)
- Professor,
Biotechnology (Department of Life Technologies)

urplammi@utu.fi

+358 29 450 4587

+358 50 476 5557

Kiinamyllynkatu 10

Turku

Areas of expertise

Antibody engineering, Bioaffinity assays, in vitro diagnostics

Research

My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.

Teaching

Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics

Publications

3 of 5

Development of anti-immunocomplex specific antibodies and non-competitive time-resolved fluorescence immunoassay for the detection of estradiol (2019)
- Analytical and Bioanalytical Chemistry
Leivo J., Kivimäki L., Juntunen E., Pettersson K., Lamminmäki U.
(A1 Refereed original research article in a scientific journal)
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources (2019)
- The Journal of Applied Laboratory MedicineBiosensors
Gidwani K, Nadeem N, Huhtinen K, Kekki H, Heinosalo T, Hynninen J, Perheentupa A, Poutanen M, Carpen O, Pettersson K, Lamminmäki U
(A1 Refereed original research article in a scientific journal)
Improvement of Fab expression by screening combinatorial synonymous signal sequence librariesA cancer-specific detection of serum CA125 improves differential diagnosis of epithelial ovarian cancer from benign conditions. (2019)
- Microbial Cell FactoriesClinical Cancer Research
Kulmala A, Huovinen T, Lamminmäki U
(A1 Refereed original research article in a scientific journal)
Jobitti 2018-2020 – mitä, miksi ja miten? (2019)
- Solubiologi
Wärri A, Koulu M, Lamminmäki U, Mairinoja L, Norström A, Pietilä M, Rainio E, Salminen T, Soini S, Wittfooth S, Strauss L.
(D1 Article in a professional journal)
Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasmaCA125 glycoform assay improves the performance of conventional CA125 in the diagnostics of epithelial ovarian cancer (2019)
- PLoS ONEInternational Journal of Gynecological Cancer
Joonas Terävä, Leena Tiainen, Urpo Lamminmäki, Pirkko-Liisa Kellokumpu-Lehtinen, Kim Pettersson, Kamlesh Gidwani
(A1 Refereed original research article in a scientific journal)
Noncompetitive Chromogenic Lateral-Flow Immunoassay for Simultaneous Detection of Microcystins and Nodularin (2019)
Sultana Akter, Teemu Kustila, Janne Leivo, Gangatharan Muralitharan, Markus Vehniäinen, Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
(2018)
Huhtinen K, Gidwani K, Kekki H, Hynninen J, Salminen L, Perheentupa A, Poutanen M, Auranen A, Grenman S, Lamminmaki U, Carpen O, Pettersson KOther publication
Array-in-well epitope mapping of phage-displayed antibodies (2018) Epitope Mapping Protocols Urpo Lamminmäki, Gaurav Batra, Petri Saviranta
(A3 Refereed book chapter or chapter in a compilation book)
(2018)
Salminen L, Gidwani K, Rolfsen AL, Nadeem N, Bolstad N, Dorum A, Grenman S, Hietanen S, Perheentupa A, Poutanen M, Carpen O, Lamminmaki U, Pettersson K, Hynninen J, Huhtinen K
(Other publication)
Molecular tools for selective recovery and detection of lignin-derived molecules (2018)
- Green Chemistry
Milla Salmela, Hanna Sanmark, Elena Efimova, Alexander Efimov, Vesa P. Hytönen, Urpo Lamminmäki, Suvi Santala, Ville Santala
(A1 Refereed original research article in a scientific journal)
Array-in-well binding assay for multiparameter screening of phage displayed antibodies (2017)
- Methods
Susan Pérez-Gamarra, Liisa Hattara, Gaurav Batra, Petri Saviranta, Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
Effect of DNA sequence of Fab fragment on yield characteristics and cell growth of E-coli (2017)
- Scientific ReportsAnalytical and Bioanalytical Chemistry
Kulmala A, Huovinen T, Lamminmaki U
(A1 Refereed original research article in a scientific journal)
Non-competitive ELISA with broad specificity for microcystins and nodularinsA Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources (2017)
- Advances in Oceanography and LimnologyClinical Chemistry
Sultana Akter, Markus Vehniäinen, Jussi Meriluoto, Lisa Spoof, Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
Rapid and Highly Sensitive Non-Competitive Immunoassay for Specific Detection of Nodularin (2017)
- Microorganisms
Akter S, Vehniainen M, Kankaanpaa HT, Lamminmaki U
(A1 Refereed original research article in a scientific journal)
Super-sensitive time-resolved fluoroimmunoassay for thyroid-stimulating hormone utilizing europium(III) nanoparticle labels achieved by protein corona stabilization, short binding time, and serum preprocessing. (2017)
Näreoja T, Rosenholm JM, Lamminmäki U, Hänninen PE
(A1 Refereed original research article in a scientific journal)
(2016)
Gidwani Kamlesh, Huhtinen Kaisa, Kekki Henna, van Vliet Sandra, Hynninen Johanna, Koivuviita Niina, Perheentupa Antti, Poutanen Matti, Auranen Annika, Grenman Seija, Lamminmaki Urpo, Carpen Olli, van Kooyk Yvette, Pettersson Kim
(A1 Refereed original research article in a scientific journal)
Broad-Spectrum Noncompetitive Immunocomplex Immunoassay for Cyanobacterial Peptide Hepatotoxins (Microcystins and Nodularins) (2016)
- Analytical ChemistryBMC Biotechnology
Sultana Akter, Markus Vehniäinen, Lisa Spoof, Sonja Nybom, Jussi Meriluoto, and Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
(2016)
Kaushik N, Rohila D, Arora U, Raut R, Lamminmaki U, Khanna N, Batra G
(A1 Refereed original research article in a scientific journal)
Development of recombinant antibody-based enzyme-linked immunosorbent assay (ELISA) for the detection of skatole (2016)
- Analytical Biochemistry
Janne Leivo, Joonas Mäkela, Jaana Rosenberg, Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library – Phage display derived HDL antibodies (2016)
- Clinical Biochemistry
Priyanka Negi,Janita Lövgren,Päivi Malmi,Nina Sirkka,Jari Metso,Tuomas Huovinen,Eeva-Christine Brockmann,Kim Pettersson,Matti Jauhiainen,Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)