PhD, Adjunct Professor of Pharmacology Saku Ruohonen - UTU Research Portal

Saku Ruohonen
PhD, Adjunct Professor of Pharmacology

- Docent,
Institute of Biomedicine (Faculty of Medicine)

saturu@utu.fi

ORCID identifier: https://orcid.org/0000-0003-2503-148X

Areas of expertise

Pharmacology and toxicology. Cardiovascular sciences in preclinical and epidemiological studies.

Publications

2 of 2

TV viewing and subclinical cardiac diastolic dysfunction in early midlife. The Cardiovascular Risk in Young Finns Study. (2016) Helajärvi H, Ruohonen S, Pahkala K, Heinonen OJ, Viikari J, Raitakari OT
(Other publication)
Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice. – Noradrenergic neurone NPY and obesity (2015)
- Acta Physiologica
Vähätalo LH, Ruohonen ST, Mäkelä S, Kovalainen M, Huotari A, Mäkelä KA, Määttä JA, Miinalainen I, Gilsbach R, Hein L, Ailanen L, Mattila M, Eerola K, Röyttä M, Ruohonen S, Herzig KH, Savontaus E
(A1 Refereed original research article in a scientific journal)
Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study. (2015)
- Open Heart
Clare Arnott, Michael R Skilton, Saku Ruohonen, Markus Juonala, Jorma S A Viikari, Mika Kähönen, Terho Lehtimäki, Tomi Laitinen, David S Celermajer, Olli T Raitakari
(A1 Refereed original research article in a scientific journal)
The effects of equal caloric high fat and western diet on metabolic syndrome, oxidative stress and vascular endothelial function in mice (2014)
- Acta Physiologica
I. Heinonen, P. Rinne, S. T. Ruohonen, S. Ruohonen, M. Ahotupa, E. Savontaus
(A1 Refereed original research article in a scientific journal)
A polymorphism in the protein kinase C gene PRKCB is associated with alpha(2)-adrenoceptor-mediated vasoconstriction (2013)
- Pharmacogenetics and Genomics
Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A
(A1 Refereed original research article in a scientific journal)
Lentivirus-Mediated alpha-Melanocyte-Stimulating Hormone Overexpression in the Hypothalamus Decreases Diet Induced Obesity in Mice (2013)
- Journal of Neuroendocrinology
Eerola K, Nordlund W, Virtanen S, Dickens AM, Mattila M, Ruohonen ST, Chua SC Jr, Wardlaw SL, Savontaus M, Savontaus E
(A1 Refereed original research article in a scientific journal)
Pharmacological treatment with a melanocortin analogue protects against pressure-overload-induced cardiac hypertrophy (2013)
- FASEB Journal
Faseb Journal Rinne P, Ruohonen ST, Ruohonen S, Savontaus E
(Other publication)
Status epilepticus alters neurogenesis and decreases the number of GABAergic neurons in the septal dentate gyrus of 9-day-old rats at the early phase of epileptogenesis (2013)
- Brain Research
Lauren HB, Ruohonen S, Kukko-Lukjanov TK, Virta JE, Gronman MA, Lopez-Picon FR, Jarvela JT, Holopainen IE
(A1 Refereed original research article in a scientific journal)
α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction (2013)
- Cardiovascular Research
Petteri Rinne, Wendy Nordlund, Ilkka Heinonen, Anna-Maija Penttinen, Antti Saraste, Suvi T. Ruohonen, Satu Mäkelä, Laura Vähätalo, Katja Kaipio, Minying Cai, Victor J. Hruby, Saku Ruohonen, Eriika Savontaus
(A1 Refereed original research article in a scientific journal)
Involvement of α2-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia. (2012)
- Neuroendocrinology
Ruohonen ST, Ruohonen S, Gilsbach R, Savontaus E, Scheinin M, Hein L
(A1 Refereed original research article in a scientific journal)
Neuropeptide Y in the noradrenergic neurons induces the development of cardiometabolic diseases in a transgenic mouse model (2012) Ruohonen Saku Tuomas, Pesonen Ullamari, Savontaus Eriika
(A1 Refereed original research article in a scientific journal)
Dietary sodium modulates the interaction between efferent and afferent renal nerve activity by altering activation of α2-adrenoceptors on renal sensory nerves (2011)
- AJP - Regulatory, Integrative and Comparative Physiology
Kopp UC, Cicha MZ, Smith LA, Ruohonen S, Scheinin M, Fritz N, Hökfelt T
(A1 Refereed original research article in a scientific journal)
Dorsal hand vein responses to the α₁-adrenoceptor agonist phenylephrine do not predict responses to the α₂-adrenoceptor agonist dexmedetomidine. (2011)
- European Journal of Pharmacology
Posti JP, Valve L, Ruohonen S, Akkila J, Scheinin M, Snapir A
(A1 Refereed original research article in a scientific journal)
Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: Treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death (2011)
- Neuropharmacology
Jarvela JT, Ruohonen S, Kukko-Lukjanov TK, Plysjuk A, Lopez-Picon FR, Holopainen IE
(A1 Refereed original research article in a scientific journal)
Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus (2011)
- Journal of Neuroinflammation
Jarvela JT, Lopez-Picon FR, Plysjuk A, Ruohonen S, Holopainen IE
(A1 Refereed original research article in a scientific journal)
Sympathetic nervous system-targeted neuropeptide Y overexpression in mice enhances neointimal formation in response to vascular injury. (2009)
- Peptides
Ruohonen ST, Abe K, Kero M, Toukola L, Ruohonen S, Röyttä M, Koulu M, Pesonen U, Zukowska Z, Savontaus E
(A1 Refereed original research article in a scientific journal)
Cytokine responses during chronic denervation. (2005)
- Journal of Neuroinflammation
Ruohonen S, Khademi M, Jagodic M, Taskinen HS, Olsson T, Röyttä M
(A1 Refereed original research article in a scientific journal)
Distinct expression of TGF-beta1 mRNA in the endo- and epineurium after nerve injury. (2004)
- Journal of Neurotrauma
Taskinen HS, Ruohonen S, Jagodic M, Khademi M, Olsson T, Röyttä M
(A1 Refereed original research article in a scientific journal)
Bioplasticity after peripheral nerve injury (2003) Röyttä M, Taskinen H-S, Siironen J, Vuorinen V, Ruohonen S
(A2 Refereed review article in a scientific journal )
Contralateral non-operated nerve to transected rat sciatic nerve shows increased expression of IL-1beta, TGF-beta1, TNF-alpha, and IL-10. (2002)
- Journal of Neuroimmunology
Ruohonen S, Jagodi M, Khademi M, Taskinen HS, Ojala P, Olsson T, Röyttä M
(A1 Refereed original research article in a scientific journal)