PhD, Adjunct Professor in Cancer Biology Kaisa Huhtinen - UTU Research Portal

Kaisa Huhtinen
PhD, Adjunct Professor in Cancer Biology

- Docent,
Faculty of Medicine (University of Turku)

kaisa.huhtinen@utu.fi

+358 29 450 2645

+358 50 572 6733

Kiinamyllynkatu 10

Turku

: D5038

: https://orcid.org/0000-0001-9685-5246

ResearchGate_Kaisa_Huhtinen

Ovarian cancer; personalized medicine; early diagnostics; prediction; prognosis; biomarker; genomics; drug target; interdicipline research;

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CA125 glycoform assay improves the performance of conventional CA125 in the diagnostics of epithelial ovarian cancer (2018)
- International Journal of Gynecological Cancer
Salminen L, Gidwani K, Rolfsen AL, Nadeem N, Bolstad N, Dorum A, Grenman S, Hietanen S, Perheentupa A, Poutanen M, Carpen O, Lamminmaki U, Pettersson K, Hynninen J, Huhtinen K
High-throughput screening of new potential targets for high-grade serous ovarian cancer treatment (2018)
- Clinical Cancer Research
Dai J, Erkan EP, Zhang KY, Kaipio K, Lamminen T, Huhtinen K, Hynninen J, Grenman S, Carpen OM, Hautaniemi S, Vaharautio A
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis (2018)
- Human Reproduction
Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala TD, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer (2018)
- Oncology
Kemiläinen H., Huhtinen K., Auranen A., Carpén O., Strauss L., Poutanen M.
DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer (2017)
- Scientific Reports
Riikka J. Lund, Kaisa Huhtinen, Jussi Salmi, Juha Rantala, Elizabeth V. Nguyen, Robert Moulder, David R. Goodlett, Riitta Lahesmaa, Olli Carpén
Hyper-phosphorylation of Sequestosome-1 Distinguishes Resistance to Cisplatin in Patient Derived High Grade Serous Ovarian Cancer Cells (2017)
- Molecular and Cellular Proteomics
Nguyen Elizabeth V, Huhtinen Kaisa, Goo Young Ah, Kaipio Katja, Andersson Noora, Rantanen Ville, Hynninen Johanna, Lahesmaa Riitta, Carpen Olli, Goodlett David R
Uusi lektiini-avusteinen määrityskonsepti parantamaan CA-125-kasvainmerkkiaineen munasarjasyöpäspesifisyyttä (2017)
- Kliin lab
Kekki H, Gidwani K, Huhtinen K, Hynninen J, Pettersson K
A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources (2016)
- Clinical Chemistry
Gidwani Kamlesh, Huhtinen Kaisa, Kekki Henna, van Vliet Sandra, Hynninen Johanna, Koivuviita Niina, Perheentupa Antti, Poutanen Matti, Auranen Annika, Grenman Seija, Lamminmaki Urpo, Carpen Olli, van Kooyk Yvette, Pettersson Kim
Characterization of ascites and tumor-derived ovarian cancer stem-like cells (2016)
- Clinical Cancer Research
Kaipio K, Chen P, Huhtinen K, Mikkonen P, Ostling P, Mpindi JP, Lehtinen L, Roering P, Korpela T, Wennerberg K, Yadav B, Aittokallio T, Kulesskiy E, Hynninen J, Auranen A, Grenman S, Hautaniemi S, Carpen O
Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to paclitaxel (2016)
- Oncotarget
Mahesh Tambe, Sofia Pruikkonen, Jenni Mäki-Jouppila, Ping Chen,
Bente Vilming Elgaaen, Anne Hege Straume, Kaisa Huhtinen, Olli Cárpen, Per
Eystein Lønning, Ben Davidson, Sampsa Hautaniemi, Marko J. Kallio
Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy (2015)
- Cancer Research
Chen P, Huhtinen K, Kaipio K, Mikkonen P, Aittomaki V, Lindell R, Hynninen J, Auranen A, Grenman S, Lehtonen R, Carpen O, Hautaniemi S
High-grade serous ovarian cancer subtyping identifies pathways for targeted therapy (2014)
- European Journal of Cancer
Huhtinen K, Chen P, Mikkonen P, Kaipio K, Aittomaki V, Lindell R, Auranen A, Lehtonen R, Hautaniemi S, Carpen O
Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions (2014)
- Journal of Clinical Endocrinology and Metabolism
Huhtinen K, Saloniemi-Heinonen T, Keski-Rahkonen P, Desai R, Laajala D, Ståhle M, Häkkinen M, Laajala D, Suvitie P, Awosanya M, Aittokallio T, Handelsman D, Auriola S, Perheentupa A, Poutanen M.
Ovarian Endometriosis Signatures Established through Discovery and Directed Mass Spectrometry Analysis (2014)
- Journal of Proteome Research
Vehmas AP, Muth-Pawlak D, Huhtinen K, Saloniemi-Heinonen T, Jaakkola K, Laajala TD, Kaprio H, Suvitie PA, Aittokallio T, Siitari H, Perheentupa A, Poutanen M, Corthals GL
Serum concentrations of HE4 change little during in vitro fertilization. (2014)
- Acta Obstetricia et Gynecologica Scandinavica
Hallamaa M, Huhtinen K, Suvitie P, Perheentupa A
Characterization of primary high-grade serous ovarian cancer cell lines: Cell line and growth condition specific differences in stem cell marker expression and high-throughput drug screening (2013)
- Clinical Cancer Research
Roering P, Mikkonen P, Kaipio K, Huhtinen K, Hynninen J, Auranen A, Kulesskiy E, Yadav B, Aittokallio T, Grenman S, Wennerberg K, Carpen O
LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization (2013)
- Journal of Mass Spectrometry
Keski-Rahkonen P, Huhtinen K, Desai R, Harwood DT, Handelsman DJ, Poutanen M, Auriola S
Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels. (2012)
- Journal of Clinical Endocrinology and Metabolism
Huhtinen K, Desai R, Ståhle M, Salminen A, Handelsman DJ, Perheentupa A, Poutanen M.
Estrogen biosynthesis and signaling in endometriosis (2012)
- Molecular and Cellular Endocrinology
Huhtinen K, Ståhle M, Perheentupa A, Poutanen M
Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterne myocytes (2012)
- Journal of Cellular and Molecular Medicine
Lee Yun, Sooranna Suren R, Terzidou Vasso, Christian Mark, Brosens Jan, Huhtinen Kaisa, Poutanen Matti, Barton Geraint, Johson Mark R, Bennet Phillip R