Kaisa Huhtinen
PhD, Adjunct Professor in Cancer Biology
Ovarian cancer; personalized medicine; early diagnostics; prediction; prognosis; biomarker; genomics; drug target; interdicipline research;
- FUNGI: Fusion Gene Integration Toolset (2021) Cervera Alejandra, Rausio Heidi, Kähkönen Tiia, Andersson Noora, Partel Gabriele, Rantanen Ville, Paciello Giulia, Ficarra Elisa, Hynninen Johanna, Hietanen Sakari, Carpén Olli, Lehtonen Rainer, Hautaniemi Sampsa, Huhtinen Kaisa
- Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy (2021) Iyer Sonia, Zhang Shuang, Yucel Simge, Horn Heiko, Smith Sean G, Reinhardt Ferenc, Hoefsmit Esmee, Assatova Bimarzhan, Casado Julia, Meinsohn Marie-Charlotte, Barrasa M Inmaculada, Bell George W, Perez-Villatoro Fernando, Huhtinen Kaisa, Hynninen Johanna, Oikkonen Jaana, Galhenage Pamoda M, Pathania Shailja, Hammond Paula T, Neel Benjamin G, Färkkilä Anniina, Pépin David, Weinberg Robert A.
- Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer (2021)
- Briefings in Bioinformatics
He Liye, Bulanova Daria, Oikkonen Jaana, Häkkinen Antti, Zhang Kaiyang, Zheng Shuyu, Wang Wenyu, Erkan Erdogan Pekcan, Carpén Olli, Joutsiniemi Titta, Hietanen Sakari, Hynninen Johanna, Huhtinen Kaisa, Hautaniemi Sampsa, Vähärautio Anna, Tang Jing, Wennerberg Krister, Aittokallio Tero
- PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples (2021) Häkkinen Antti, Zhang Kaiyang, Alkodsi Amjad, Andersson Noora, Pekcan Erkan Erdogan, Dai Jun, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Vähärautio Anna, Carpén Olli, Hynninen Johanna, Hietanen Sakari, Lehtonen Rainer, Hautaniemi Sampsa
- Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition (2021) Siddiqui Arafat, Tumiati Manuela, Joko Alia, Sandholm Jouko, Roering, Aakko Pia Sofia, Vainionpää Reetta, Kaipio Katja, Huhtinen Kaisa, Kauppi Liisa, Tuomela Johanna, Hietanen Sakari
- ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors (2020) Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén
- A longitudinal analysis of CA125 glycoforms in the monitoring and follow up of high grade serous ovarian cancer (2020) Liina Salminen, Nimrah Nadeem, Shruti Jain, Seija Grènman, Olli Carpén, Sakari Hietanen, Sinikka Oksa, Urpo Lamminmäki, Kim Pettersson, Kamlesh Gidwani, Kaisa Huhtinen, Johanna Hynninen
- American Association for Cancer Research Special Conference on Advances in Ovarian Cancer Research Sep 13-16, 2019 Atlanta, GA, USA Abstracts (2020) Oikkonen J, Sanz NC, Hakkinen A, Li YL, Schulman I, Kivikoski M, Huhtinen K, Hietanen S, Grenman SE, Hynninen J, Lehtonen R, Hautaniemi S
- Analysis of single-cell RNA-seq data from ovarian cancer samples before and after chemotherapy links stress-related transcriptional profile with chemotherapy resistance (2020) Zhang K, Erkan EP, Dai J, Andersson N, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Carpen O, Hynninen J, others
- A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions (2020) Gabriel M, Fey V, Heinosalo T, Adhikari P, Rytkönen K, Komulainen T, Huhtinen K, Laajala TD, Siitari H, Virkki A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M
- Exploratory Analysis of CA125-MGL and –STn Glycoforms in the Differential Diagnostics of Pelvic Masses (2020)
- The Journal of Applied Laboratory Medicine
Liina Salminen, Nimrah Nadeem, Anne Lone Rolfsen, Anne Dørum, Teemu D Laajala, Seija Grènman, Sakari Hietanen, Taija Heinosalo, Antti Perheentupa, Matti Poutanen, Nils Bolstad, Olli Carpén, Urpo Lamminmäki, Kim Pettersson, Kamlesh Gidwani, Johanna Hynninen, Kaisa Huhtinen
- Glycovariant-based lateral flow immunoassay to detect ovarian cancer–associated serum CA125 (2020) Sherif Bayoumy, Heidi Hyytiä, Janne Leivo, Sheikh M. Talha, Kaisa Huhtinen, Matti Poutanen, Johanna Hynninen, Antti Perheentupa, Urpo Lamminmäki, Kamlesh Gidwani & Kim Pettersson
- HE4 in the evaluation of tumor load and prognostic stratification of high grade serous ovarian carcinoma (2020) Liina Salminen, Kamlesh Gidwani, Seija Grènman, Olli Carpén, Sakari Hietanen, Kim Pettersson, Kaisa Huhtinen, Johanna Hynninen
- RNA-seq analysis of high-grade serous ovarian cancer patients before and after chemotherapy reveals chemoresistance-associated genes and pathways (2020) Jamalzadeh S, Zhang KY, Hakkinen A, Huhtinen K, Hynninen J, Andersson N, Mansuri N, Carpen O, Erdogan E, Dai J, Vaharautio A, Hietanen S, Oikkonen J, Lehtonen R, Hautaniemi S
- Singling out tumor heterogeneity and chemoresistance in high-grade serous ovarian cancer (2020) Erkan EP, Dai J, Zhang KY, Kaipio K, Lamminen T, Mansuri N, Suominen L, Alkodsi A, Huhtinen K, Hietanen S, Hynninen J, Grenman S, Carpen O, Hautaniemi S, Vaharautio A
- CtDNA profiling to predict prognosis and optimize treatment in high-grade serous ovarian cancer (2019) Oikkonen J, Zhang KY, Salminen L, Huhtinen K, Schulman I, Andersson N, Carpen O, Hietanen S, Grenman S, Lehtonen R, Hynninen J, Farkkila A, Hautaniemi S
- Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources (2019)
- The Journal of Applied Laboratory Medicine
Gidwani K, Nadeem N, Huhtinen K, Kekki H, Heinosalo T, Hynninen J, Perheentupa A, Poutanen M, Carpen O, Pettersson K, Lamminmäki U
- Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer (2019) Oikkonen J, Zhang KY, Salminen L, Schulman I, Lavikka K, Andersson N, Ojanperä E, Hietanen S, Grenman S, Lehtonen R, Huhtinen K, Carpen O, Hynninen J, Färkkilä A, Hautaniemi S
- A cancer-specific detection of serum CA125 improves differential diagnosis of epithelial ovarian cancer from benign conditions. (2018) Huhtinen K, Gidwani K, Kekki H, Hynninen J, Salminen L, Perheentupa A, Poutanen M, Auranen A, Grenman S, Lamminmaki U, Carpen O, Pettersson K
- A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients (2018) Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Grénman S, Vähärautio A, Carpén O, Kauppi L
