Kaisa Huhtinen
PhD, Adjunct Professor in Cancer Biology
Ovarian cancer; personalized medicine; early diagnostics; prediction; prognosis; biomarker; genomics; drug target; interdicipline research;
- Circulating tumor DNA-based copy-number profiles enable monitoring treatment effects during therapy in high-grade serous carcinoma (2023)
- Biomedicine and Pharmacotherapy
Nguyen Mai TN, Rajavuori Anna, Huhtinen Kaisa, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa
- Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma (2023) Lahtinen Alexandra, Lavikka Kari, Virtanen Anni, Li Yilin, Jamalzadeh Sanaz, Skorda Aikaterini, Lauridsen Anna Rössberg, Zhang Kaiynag, Marchi Giovanni, Isoviita Veli-Matti, Ariotta Valeria, Lehtonen Oskari, Muranen Taru A., Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Senkowski Wojciech, Kallunki Tuula, Häkkinen Aantti, Hynninen Johanna, Oikkonen Jaana, Hautaniemi Sampsa
- Quantification of cell death and proliferation of patient-derived ovarian cancer organoids through 3D imaging and image analysis (2023) Skorda Aikaterini, Lauridsen Anna Rossberg, Huhtinen Kaisa, Lahtinen Alexandra, Senkowski Wojciech, Oikkonen Jaana, Hynninen Johanna, Hautaniemi Sampsa, Kallunki Tuula
- Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high-grade serous ovarian cancer (2023)
- Basic and Clinical Pharmacology and Toxicology
Deng Feng, Laasik Maren, Salminen Liina, Lapatto Lauri, Huhtinen Kaisa, Li Yilin, Hautaniemi Sampsa, Hynninen Johanna, Niemi Mikko, Lehtonen Rainer
- Diagnostic potential of nanoparticle aided assays for MUC16 and MUC1 glycovariants in ovarian cancer (2022)
- International Journal of Cancer
Jain Shruti, Nadeem Nimrah, Ulfenborg Benjamin, Mäkelä Maria, Ruma Shamima Afrin, Terävä Joonas, Huhtinen Kaisa, Leivo Janne, Kristjansdottir Björg, Pettersson Kim, Sundfeldt Karin, Gidwani Kamlesh
- Dubious effects of methadone as an “anticancer” drug on ovarian cancer cell-lines and patient-derived tumor-spheroids (2022) Fiegl Heidelinde, Hagenbuchner Judith, Kyvelidou Christiana, Seeber Beata, Sopper Sieghart, Tsibulak Irina, Wieser Verena, Reiser Elisabeth, Roessler Julia, Huhtinen Kaisa, Carpén Olli, Parson Walther, Sprung Susanne, Marth Christian, Ausserlechner Michael J., Zeimet Alain G.
- Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status (2022) Roering Pia, Siddiqui Arafat, Heuser Vanina D, Potdar Swapnil, Mikkonen Pia, Oikkonen Jaana, Li Yilin, Pikkusaari Sanna, Wennerberg Krister, Hynninen Johanna, Grenman Seija, Huhtinen Kaisa, Auranen Annika, Carpén Olli, Kaipio Katja
- Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer (2022) Zhang Kaiyang, Erkan Erdogan Pekcan, Jamalzadeh Sanaz, Dai Jun, Andersson Noora, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Oikkonen Jaana, Hynninen Johanna, Virtanen Anni, Häkkinen Antti, Hautaniemi Sampsa, Vähärautio Anna
- Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)
- Molecular Cancer Therapeutics
Cvrljevic Anna N., Butt Umar, Huhtinen Kaisa, Grönroos Tove J., Böckelman Camilla, Lassus Heini, Butzow Ralf, Haglund Caj, Kaipio Katja, Arsiola Tiina, Laajala Teemu D., Connolly Denise C, Ristimäki Ari, Carpen Olli, Pouwels Jeroen, Westermarck Jukka
- QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability (2022) Jamalzadeh Sanaz, Häkkinen Antti, Andersson Noora, Huhtinen Kaisa, Laury Anna, Hietanen Sakari, Hynninen Johanna, Oikkonen Jaana, Carpén Olli, Virtanen Anni, Hautaniemi Sampsa
