Jyrki Heino - UTU Research Portal

Jyrki Heino

- Professor,
Biochemistry (Department of Life Technologies)
- ,
InFLAMES Flagship (Faculty of Medicine)

jyheino@utu.fi

+358 29 450 2197

+358 50 523 8351

Tykistökatu 6

Turku

: https://orcid.org/0000-0003-2978-805X

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Integrin alpha 11 beta 1 is a receptor for collagen XIII (2020)
- Cell and Tissue Research
Koivunen J, Tu H, Kemppainen A, Anbazhagan P, Finnila MA, Saarakkala S, Kapyla J, Lu N, Heikkinen A, Juffer AH, Heino J, Gullberg D, Pihlajaniemi T
Interaction between prostate cancer cells and prostate fibroblasts promotes accumulation and proteolytic processing of basement membrane proteins (2020)
- Prostate
Ojalill M, Virtanen N, Rappu P, Siljamäki E, Taimen P, Heino J
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine (2020)
- Journal of Extracellular Vesicles
Dhondt B, Geeurickx E, Tulkens J, Van Deun J, Vergauwen G, Lippens L, Miinalainen I, Rappu P, Heino J, Ost P, Lumen N, De Wever O, Hendrix A
Biokemia ja solubiologia (2019) Jyrki Heino, Matti Vuento
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy (2019)
- eLife
Osterman CJD, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang SL, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu GR, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD, Schlaepfer DD
Role of prolyl hydroxylation in the molecular interactions of collagens (2019)
- Essays in Biochemistry
Rappu P., Salo A., Myllyharju J., Heino J.
Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells (2018)
- Scientific Reports
Anandi Rajan, B. David Persson, Lars Frängsmyr, Annelie Olofsson, Linda Sandblad, Jyrki Heino, Yoshikazu Takada, A. Paul Mould, Lynn M. Schnapp, Jason Gall, Niklas Arnberg
Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells (2018)
- Oncotarget
Ojalill M., Parikainen M., Rappu P., Aalto E., Jokinen J., Virtanen N., Siljamäki E., Heino J.
Long non-coding RNA PICSAR decreases adhesion and promotes migration of squamous carcinoma cells by downregulating α2β1 and α5β1 integrin expression (2018)
- Biology Open
Minna Piipponen, Jyrki Heino, Veli-Matti Kähäri, Liisa Nissinen
Ontuvan luutnantin matkassa Porthanin päiviin (2018)
- Auraica: Scripta A Societate Porthan Edita
Jyrki Heino
Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms (2018)
- Journal of Biological Chemistry
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
- Prostate
Marjaana Ojalill, Pekka Rappu, Elina Siljamäki, Pekka Taimen, Peter Boström, Jyrki Heino
Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling (2017)
- Scientific Reports
Salmela Maria, Jokinen Johanna, Tiitta Silja, Rappu Pekka, Cheng Holland R, Heino Jyrki
Joint inflammation related citrullination of functional arginines in extracellular proteins (2017)
- Scientific Reports
Sipila KH, Ranga V, Rappu P, Mali M, Pirila L, Heino I, Jokinen J, Kapyla J, Johnson MS, Heino J
The binding capacity of alpha 1 beta 1-, alpha 2 beta 1-and alpha 10 beta 1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils (2017)
- Matrix Biology
Woltersdorf C, Bonk M, Leitinger B, Huhtala M, Kapyla J, Heino J, Girol CG, Niland S, Eble JA, Bruckner P, Dreier R, Hansen U
Epithelial Microvesicles Promote an Inflammatory Phenotype in Fibroblasts (2016)
- Journal of Dental Research
Bi J, Koivisto L, Owen G, Huang P, Wang Z, Shen Y, Bi L, Rokka A, Haapasalo M, Heino J, Hakkinen L, Larjava HS
Extracellular citrullination inhibits the function of matrix associated TGF-beta (2016)
- Matrix Biology
Sipila KH, Ranga V, Rappu P, Torittu A, Pirila L, Kapyla J, Johnson MS, Larjava H, Heino J
Platelet response to a small molecule inhibitor of α2β1 integrin is associated with ITGA2 C807T dimorphism. (2016)
- Platelets
Nissinen L, Rappu P, Ollikka P, Nieminen J, Marjamäki A, Heino J
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators (2016)
- Cell Stem Cell
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipila K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT
The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways (2016)
- Experimental Cell Research
Niina M. Santio, Maria Salmela, Heidi Arola, Sini K.Eerola, Jyrki Heino, Eeva-Marja Rainio, Päivi J.Koskinen