Semi Helin - UTU Research Portal - UTU Research Portal

Semi Helin

- Senior Researcher,
Turku PET Centre (Independent units)

semhel@utu.fi

Publications

3 of 4

Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation2018
- NeurologyJournal of Cerebral Blood Flow and Metabolism
Ekblad LL, Johansson J, Helin S, Viitanen M, Laine H, Puukka P, Jula A, Rinne JO
(A1 Refereed original research article in a scientific journal)
Neuroinflammation appears early and then plateaus in a mouse model of Alzheimer's disease shown by PET imaging (2018)
- Journal of Nuclear Medicine
Francisco R. López-Picón, Anniina Snellman, Olli Eskola, Semi Helin, Olof Solin, Merja Haaparanta-Solin, Juha O. Rinne
(A1 Refereed original research article in a scientific journal)
S-[F-18] THK-5117-PET and [C-11] PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-beta Plaques and Tau in Brain BiopsiesBariatric surgery normalizes brain opioid receptors (2018)
- Journal of Alzheimer's DiseaseMolecular Psychiatry
Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Heliu S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO
(A1 Refereed original research article in a scientific journal)
Applicability of [C-11]PIB micro-PET imaging for in vivo follow-up of anti-amyloid treatment effects in APP23 mouse modelWeight loss after bariatric surgery normalizes brain opioid receptors in morbid obesity (2017)
- Neurobiology of AgingMolecular Psychiatry
Snellman A, Rokka J, Lopez-Picon FR, Helin S, Re F, Löyttyniemi E, Pihlaja R, Forloni G, Salmona M, Masserini M, Solin O, Rinne JO, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Brain glucose metabolism and its relation to amyloid load in middle-aged adults with childhood-onset epilepsy (2017)
- Epilepsy Research
Juho Joutsa, Juha O. Rinne, Mira Karrasch, Bruce Hermann, Jarkko Johansson, Anu Anttinen, Olli Eskola, Semi Helin, Shlomo Shinnar, Matti Sillanpää; TACOE study group
(A1 Refereed original research article in a scientific journal)
2017
- Journal of Neuroscience
Tuulari JJ, Tuominen L, de Boer FE, Hirvonen J, Helin S, Nuutila P, Nummenmaa L
(A1 Refereed original research article in a scientific journal)
Neurotransmitters behind pain relief with transcranial magnetic stimulation - positron emission tomography evidence for release of endogenous opioids (2017)
- European Journal of Pain
Lamusuo S, Hirvonen J, Lindholm P, Martikainen IK, Hagelberg N, Parkkola R, Taiminen T, Hietala J, Helin S, Virtanen A, Pertovaara A, Jaaskelainen SK
(A1 Refereed original research article in a scientific journal)
(2016)
Karlsson HK, Tuulari JJ, Tuominen L, Hirvonen J, Honka H, Parkkola R, Helin S, Salminen P, Nuutila P, Nummenmaa L
(Other publication)
(2016)
Karlsson HK, Tuulari JJ, Tuominen L, Hirvonen J, Honka H, Parkkola R, Helin S, Salminen P, Nuutila P, Nummenmaa L
(A1 Refereed original research article in a scientific journal)
Aberrant mesolimbic dopamine-opiate interaction in obesityDimeric [68Ga]DOTA-RGD Peptide Targeting αvβ3 Integrin Reveals Extracellular Matrix Alterations after Myocardial Infarction (2015)
- NeuroImageMolecular Imaging and Biology
Tuominen L, Tuulari J, Karlsson H, Hirvonen J, Helin S, Salminen P, Parkkola R, Hietala J, Nuutila P, Nummenmaa L
(A1 Refereed original research article in a scientific journal)
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease[11C]PIB, [18F]FDG and MR imaging in patients with mild cognitive impairment (2015)
- BrainEuropean Journal of Nuclear Medicine and Molecular Imaging
Jucaite A, Svenningsson P, Rinne JO, Cselenyi Z, Varnas K, Johnstrom P, Amini N, Kirjavainen A, Helin S, Minkwitz M, Kugler AR, Posener JA, Budd S, Halldin C, Varrone A, Farde L
(A1 Refereed original research article in a scientific journal)
Lihavuus on yhteydessä opioidijärjestelmän muutokseenAdenosine A2A receptors in secondary progressive multiple sclerosis: a [C-11]TMSX brain PET study (2015)
- Duodecim
Karlsson Henry K, Tuominen Lauri, Tuulari Jetro J, Hirvonen Jussi, Parkkola Riitta, Helin Semi, Salminen Paulina, Nuutila Pirjo, Nummenmaa Lauri
(Other publication)
Obesity Is Associated with Decreased mu-Opioid But Unaltered Dopamine D-2 Receptor Availability in the Brain (2015)
- Journal of Neuroscience
Karlsson HK, Tuominen L, Tuulari JJ, Hirvonen J, Parkkola R, Helin S, Salminen P, Nuutila P, Nummenmaa L
(A1 Refereed original research article in a scientific journal)
Test-retest reliability of (11)C-ORM-13070 in PET imaging of α2C-adrenoceptors in vivo in the human brain (2015)
- European Journal of Nuclear Medicine and Molecular Imaging
Jussi Lehto, Jere R. Virta, Vesa Oikonen, Anne Roivainen, Pauliina Luoto, Eveliina Arponen, Semi Helin, Johanna Hietamäki, Aila Holopainen, Marita Kailajärvi, Juha M. Peltonen, Juha Rouru, Jukka Sallinen, Kirsi Virtanen, Iina Volanen, Mika Scheinin, Juha O. Rinne
(A1 Refereed original research article in a scientific journal)
¹¹C-ORM-13070, a novel PET ligand for brain α₂C-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men. (2014)
- European Journal of Nuclear Medicine and Molecular Imaging
Luoto P, Suilamo S, Oikonen V, Arponen E, Helin S, Herttuainen J, Hietamäki J, Holopainen A, Kailajärvi M, Peltonen JM, Rouru J, Sallinen J, Scheinin M, Virta J, Virtanen K, Volanen I, Roivainen A, Rinne JO
(A1 Refereed original research article in a scientific journal)
6-[18F]Fluoro-l-DOPA Uptake in the Rat Pancreas is Dependent on the Tracer Metabolism (2014)
- Molecular Imaging and Biology
Kalliokoski T, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Gronroos TJ, Solin O, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
A PET Tracer for Brain α2C Adrenoceptors, 11C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice (2014)
- Journal of Nuclear Medicine
Arponen E, Helin S, Marjamäki P, Grönroos T, Holm P, Löyttyniemi E, Någren K, Scheinin M, Haaparanta-Solin M, Sallinen J, Solin O
(A1 Refereed original research article in a scientific journal)
(2014)
Kiugel M, Dijkgraaf I, Kytö V, Helin S, Liljenbäck H, Saanijoki T, Yim CB, Oikonen V, Saukko P, Knuuti J, Roivainen A, Saraste A
(A1 Refereed original research article in a scientific journal)
(2013)
Brück A, Virta JR, Koivunen J, Koikkalainen J, Scheinin NM, Helenius H, Någren K, Helin S, Parkkola R, Viitanen M, Rinne JO
(A1 Refereed original research article in a scientific journal)
(2013)
Rissanen E, Virta JR, Paavilainen T, Tuisku J, Helin S, Luoto P, Parkkola R, Rinne JO, Airas L
(A1 Refereed original research article in a scientific journal)