Jorma Määttä
PhD., Adjunct Professor
Turun tautimallinnuskeskus TCDM jmaatta@utu.fi +358 29 450 4466 +358 50 400 4219 Kiinamyllynkatu 10 Turku Office: C411 ORCID identifier: https://orcid.org/0000-0001-8752-6862 |
myeloid cells; chronic inflammation; sex steroid receptor; bone biology; tumor macrophage; bioimaging
ADMIO -consortium and IPP / drug research and development. TCDM
Education and degrees completed
Doctor of Philosophy 17.8.1998, University of Turku, Medical Faculty
Master of Science 11.3.1993, University of Turku, Biotechnology
High school graduation 31.5.1987, Rauhala High School, Lieksa
Military service 13.6 1988 – 8.5.1989, SissiK/P-KR
Title of Docent 27.3.2006 Docent (Adjunct Professor) of Molecular Cell Biology, Institute of Biochemistry, University of Turku.
Other education
21.6.2018 Official teacher’s qualification (decree 794/2004; 60 credits ECTS B), University of Turku, Faculty of Education Radiation safety principal, 2007, University of Helsinki
Current position University Lecturer, Principal Investigator, University of Turku, Institute of Biomedicine 1.1.2018 -
Previous work experience
1.1.2016 – 31.12.2017 University Research Fellow at the University of Turku, Institute of Biomedicine
1.9.2011 – 31.12.2015 University Research Fellow at the University of Turku, Department of Cell Biology and Anatomy (50%) and the University of Eastern Finland, School of Pharmaceutics (50%)
1.9. 2007 – 31.8.2011 Senior Scientist, Bone Analysis Unit Manager of Turku Center for Disease Modeling
1.1.2006 – 31.8.2007 Senior Scientist, Professor Kalervo Väänänen’s research group, Department of Anatomy, University of Turku
1.9.2005 – 31.12.2005 Senior Scientist, Professor Pirkko Härkönen’s research group, Department of Anatomy, University of Turku
1.1.2004 – 31.8.2005 Senior Scientist, Docent Markku Salmivirta’s research group Turku Centre of Biotechnology
1.8.2003 – 31.12.2003 Postdoctoral Researcher in Docent Klaus Elenius’s research group, Medicity Research Laboratory, University of Turku
1.8.2002 – 31.7.2003 Postdoctoral Researcher of the Foundation of the Finnish Cancer Institute
1.8.1999 – 31.7.2002 Postdoctoral Researcher of the Academy of Finland
1.1.1999 – 31.12.2004 Postdoctoral Researcher in Docent Klaus Elenius’s research group, Medicity Research Laboratory, University of Turku
1.7.1998 – 31.12.1998 Research Fellow in Docent Ari Hinkkanen’s research group Department of Biochemistry and Pharmacy, Åbo Akademi University
1.2.1995 – 30.6.1998 Turku Post Graduate School of Biomed. Sciences, post graduate student
1.1.1993 – 31.1.1995 Research assistant, Department of Virology, University of Turku
1991, 1992, 1.6-31.8. Research assistant, Department of Virology, University of Turku
4.6.1990 – 31.8.1990 Research assistant, Huhtamäki Oy Leiras Ltd. Biotechnological Research Laboratory
In my research, the function of myeloid cells and mesenchymal cells in the process of calvarial implant integration (ADMIO-consortium). Further, we study also the role of sex steroid receptors on regulation of myeloid cells. This includes the role of myeloid cells in chronic inflammations (e.g. chronic colitis) as well as in tumors.
Teaching responsibilities include lecturing and contact teaching on the fields of (molecular) cell biology and histology for medical, biomedical and dentistry students
- Tsoledronaatti toimii tehokkaasti rintasyöpäsoluissa liposomaalisena tai kalsiumiin sitoutuneena (2016)
- BestPractice Onkologia ja hematologia
(Other publication) - Uptake of free, calcium-bound and liposomal encapsulated nitrogen containing bisphosphonates by breast cancer cells (2016)
- European Journal of Pharmaceutical Sciences
(A1 Refereed original research article in a scientific journal) - Human breast cancer cells educate macrophages toward the M2 activation status. (2015)
- Breast Cancer Research
(A1 Refereed original research article in a scientific journal) - Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells. (2015)
- BMC Cancer
(A1 Refereed original research article in a scientific journal) - Macrophages and pathophysiology of bone cancers (2015) Bone Cencer: Primary Bone Cancer and Bone Metastasis, 2nd Ed. Sofia Sousa, Jorma A. Määttä
(A3 Refereed book chapter or chapter in a compilation book) - Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice. – Noradrenergic neurone NPY and obesity (2015)
- Acta Physiologica
(A1 Refereed original research article in a scientific journal) - Overexpression of spermidine/spermine N1-acetyltransferase impairs osteoblastogenesis and alters mouse bone phenotype. (2015)
- Transgenic Research
(A1 Refereed original research article in a scientific journal) - Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells (2015)
- Cancer Letters
(A1 Refereed original research article in a scientific journal) - Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. (2014)
- Molecular Cancer
(A1 Refereed original research article in a scientific journal) - Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages. (2013)
- Journal of Experimental Medicine
(A1 Refereed original research article in a scientific journal)



