Pekka Taimen
MD, PhD
pepeta@utu.fi +358 29 450 4524 +358 50 431 1353 Kiinamyllynkatu 10 Turku Office: D5019 ORCID identifier: https://orcid.org/0000-0001-8849-4604 Official web page of research group |
pathology; histology; cell biology; prostate cancer, bladder cancer, cardiomyopathy, nuclear lamin
Pekka Taimen received his MD degree from the University of Turku in 2001 and defended his thesis at the Department of Pathology, University of Turku in 2004. In 2008-2009 PT worked as a postdoctoral fellow in the laboratory of Prof. Robert D. Goldman, Northwestern University Medical School, Chicago. Postdoctoral studies focusing on nuclear intermediate filament proteins called lamins were further continued as a junior group leader after returning back to Turku in early 2010. In 2011 PT received a specialist degree in Pathology and since then he has worked as a part-time specialist at the Pathology Division, Turku University Hospital with special focus on uropathology. From 2012 PT has worked as a Clinical lecturer in Pathology and between 2015-2019 as a part-time Academy of Finland Clinical Researcher. PT was appointed as a tenure track Assistant Professor of Molecular Pathology in January 2019 and an Associate Professor in August 2020. In January 2022, PT was appointed as a Professor of Molecular Pathology and he currently serves as the head of the pathology unit at the Faculty of Medicine, University of Turku.
Professor Pekka Taimen has 20 years of experience in cell and molecular biology as well as in translational research. The main focus of his research group is on human diseases caused by lamin mutations, such as cardiomyopathies and premature aging syndrome. More recently, PT has also actively worked on prostate and bladder cancer related projects including novel biomarkers, biobanking, patient derived cell lines and improved imaging techniques utilizing digital pathology and machine learning approaches.
Pekka Taimen has more than 10 years of experience in teaching medical students at the Institute of Biomedicine, University of Turku. He has served first as a university teacher and from 2012 as a clinical lecturer. In 2015 PT received the Lecturer of the Year award in the Faculty of Medicine.
- Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial) (2018)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - Radiomic features from pretreatment biparametric MRI predict prostate cancer biochemical recurrence: Preliminary findingsEstablishment of a realistic patient derived xenograft (PDX) model for prostate cancer bone metastasis (2018)
- Journal of Magnetic Resonance Imaging
(A1 Refereed original research article in a scientific journal) - The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysisGlobal expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate (2018)
- ProstateBMC Urology
(A1 Refereed original research article in a scientific journal) - Increased expression of fibroblast growth factor 13 in prostate cancer is associated with shortened time to biochemical recurrence after radical prostatectomy (2017)
- Magnetic Resonance in MedicineCancer Research
- Immunological tumor status may predict response to neoadjuvant chemotherapy and outcome after radical cystectomy in bladder cancerInternal epithelia in Drosophila display rudimentary competence to form cytoplasmic networks of transgenic human vimentin (2017)
- Scientific ReportsFASEB Journal
(A1 Refereed original research article in a scientific journal) - Increased FGFRL1 expression is associated with prostate cancer progression (2017)
(Other publication) - (2017)
(A1 Refereed original research article in a scientific journal) - Nestin contributes to skeletal muscle homeostasis and regenerationRelaxation along fictitious field, diffusion-weighted imaging, and T2 mapping of prostate cancer: Prediction of cancer aggressiveness (2017)
- Journal of Cell ScienceMagnetic Resonance in Medicine
(A1 Refereed original research article in a scientific journal) - Novel Biparametric MRI and Targeted Biopsy Improves Risk Stratification in Men With a Clinical Suspicion of Prostate Cancer (IMPROD Trial)Rotating frame relaxation imaging of prostate cancer: Repeatability, cancer detection, and Gleason score prediction (2017)
- Journal of Magnetic Resonance Imaging
(A1 Refereed original research article in a scientific journal) - (2017)
- Journal of Magnetic Resonance ImagingJournal of Cell Science
(A1 Refereed original research article in a scientific journal) - Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy (2016)
(A1 Refereed original research article in a scientific journal) - Diffusion Weighted Imaging of Prostate Cancer: Prediction of Cancer using Texture Features from Parametric Maps of the Monoexponential and Kurtosis functions (2016) 2016 Sixth International Conference on Image Processing Theory, Tools and Applications (IPTA) Ileana Montoya Perez, Jussi Toivonen, Parisa Movahedi, Harri Merisaari, Marko Pesola, Pekka Taimen, Peter J. Boström, Aida Kiviniemi, Hannu J. Aronen, Tapio Pahikkala, Ivan Jambor
(A4 Refereed article in a conference publication ) - (2016)
- Cancer Research
(Other publication) - (2016)
(A1 Refereed original research article in a scientific journal) - 2016
- International Journal of Cancer
(A1 Refereed original research article in a scientific journal) - Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway (2016)
- Carcinogenesis
(A1 Refereed original research article in a scientific journal) - Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy. (2016)
- Modern Pathology
(A1 Refereed original research article in a scientific journal) - Patient-specific pharmacokinetic parameter estimation on dynamic contrast-enhanced MRI of prostate: Preliminary evaluation of a novel AIF-free estimation method (2016)
- Journal of Magnetic Resonance Imaging
(A1 Refereed original research article in a scientific journal) - (2016)
(A1 Refereed original research article in a scientific journal) - (2016)
- Magnetic Resonance in Medicine
(A1 Refereed original research article in a scientific journal)



