MD, professor, Turku PET Centre Juhani Knuuti - UTU Research Portal

Juhani Knuuti
MD, professor, Turku PET Centre

- Director,
- Professor,
Turku PET Centre (Independent units)
- ,
InFLAMES Flagship (Faculty of Medicine)

jknuuti@utu.fi

+358 29 450 2345

+358 50 059 2998

Kiinamyllynkatu 4-8

Turku

: https://orcid.org/0000-0003-3156-9593

CV J Knuuti 5th February 2021_signed.pdf

Cardiovascular diseases, imaging

Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.

44 of 57

Fractal scaling properties of heart rate dynamics and myocardial efficiency in dilated cardiomyopathy (2009)
- Clinical Research in Cardiology
Salo T., Sundell J., Knuuti J., Kemppainen J., Stolen K., Nuutila P., Mäkikallio T., Huikuri H., Airaksinen K.
Imaging of vulnerable plaque: Potential breakthrough or pipe dream? (2009)
- Current Cardiovascular Imaging Reports
Laitinen I., Knuuti J.
Increased basal myocardial perfusion in patients with chronic kidney disease without symptomatic coronary artery disease (2009)
- Nephrology Dialysis Transplantation
Koivuviita N, Tertti R, Jarvisalo M, Pietila M, Hannukainen J, Sundell J, Nuutila P, Knuuti J, Metsarinne K
Integrated positron emission tomography/computed tomography (PET/CT) in coronary disease (2009)
- Heart
Knuuti J.
Liver Spill-Over Correction method for dynamic PET imaging (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
EANM 2009 Book of Abstracts Merisaari H, Han C, Nesterov S, Nevalainen O, Knuuti J
Low radiation dose imaging of myocardial perfusion and coronary angiography with a hybrid PET/CT scanner (2009)
- Clinical Physiology and Functional Imaging
Kajander S., Ukkonen H., Sipilä H., Teräs M., Knuuti J.
Myocardial perfusion quantitation with 15O-labelled water PET: High reproducibility of the new cardiac analysis software (Carimas™) (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Joutsiniemi E., Pietilä M., Knuuti J., Nesterov S., Han C., Mäki M., Kajander S., Naum A., Helenius H., Lisinen I., Ukkonen H.
Non-invasive diagnosis of acute mesenteric ischaemia using PET (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Kiss J., Naum A., Kudomi N., Knuuti J., Iozzo P., Savunen T., Nuutila P.
Non-invasive estimation of hepatic glucose uptake from [18F]FDG PET images using tissue-derived input functions (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Iozzo P., Nuutila P., Kudomi N., Järvisalo M., Kiss J., Borra R., Viljanen A., Viljanen T., Savunen T., Knuuti J., Iida H.
Prevalence of coronary artery disease assessed by multislice computed tomography coronary angiography in patients with paroxysmal or persistent atrial fibrillation (2009)
- Circulation: Cardiovascular Imaging
Heijenbrok M., Schreur J., Gaemperli O., Trines S., Kaufmann P., Turta O., Schalij M., Knuuti J., Bax J., Nucifora G., Schuijf J., Tops L., Van Werkhoven J., Kajander S., Jukema J.
Quantification of myocardial blood flow will reform the detection of CAD (2009)
- Journal of Nuclear Cardiology
Knuuti J., Kajander S., Mäki M., Ukkonen H.
Synthesis, 68Ga labeling and preliminary evaluation of DOTA peptide binding vascular adhesion protein-1: a potential PET imaging agent for diagnosing osteomyelitis (2009)
- Nuclear Medicine and Biology
Roivainen A., Jalkanen S., Ujula T., Salomäki S., Virsu P., Lankinen P., Mäkinen T., Autio A., Yegutkin G., Knuuti J.
The Adrenergic-Fatty Acid Load in Heart Failure (2009)
- Journal of the American College of Cardiology
Opie L., Knuuti J.
The effect of right ventricular pacing on myocardial oxidative metabolism and efficiency: Relation with left ventricular dyssynchrony (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Ukkonen H., Tops L., Saraste A., Naum A., Koistinen J., Bax J., Knuuti J.
The Pro12Ala polymorphism of the PPAR gamma 2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus (2009)
- Metabolism
Honka MJ, Vänttinen M, Iozzo P, Virtanen KA, Lautamäki R, Hällsten K, Borra RJ, Takala T, Viljanen AP, Kemppainen J, Pihlajamäki J, Knuuti J, Nuutila P, Laakso M
The Pro12Ala polymorphism of the PPARγ2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus (2009)
- Metabolism
Pihlajamäki J., Kemppainen J., Nuutila P., Knuuti J., Laakso M., Honka M., Vänttinen M., Iozzo P., Virtanen K., Lautamäki R., Hällsten K., Borra R., Takala T., Viljanen A.
Trimetazidine, a metabolic Modulator, has cardiac and extracardiac benefits in idiopathic dilated ardiomyopathy (2009)
- Circulation
Tuunanen H., Knuuti J., Opie L.
Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Knuuti J., Laitinen I., Marjamäki P., Någren K., Laine V., Wilson I., Leppänen P., Ylä-Herttuala S., Roivainen A.
123 I-mIBG scintigraphy to predict inducibility of ventricular arrhythmias on cardiac electrophysiology testing: a prospective multicenter pilot study. (2008)
- Circulation: Cardiovascular Imaging
Jacobson A.F., Banerjee G., Bax J.J., Kraft O., Buxton A.E., Fjeld J.G., Parízek P., Agostini D., Knuuti J., Flotats A., Arrighi J., Muxi A., Alibelli M.J.
Amino-acid-based peritoneal dialysis solution improves amino-acid transport into skeletal muscle (2008)
- Kidney International
Knuuti J., Anderstam B., Nuutila P., Metsärinne K., Asola M., Virtanen K., Någren K., Helin S., Taittonen M., Kastarinen H.