Increased basal myocardial perfusion in patients with chronic kidney disease without symptomatic coronary artery disease




Koivuviita N, Tertti R, Jarvisalo M, Pietila M, Hannukainen J, Sundell J, Nuutila P, Knuuti J, Metsarinne K

PublisherOXFORD UNIV PRESS

2009

Nephrology Dialysis Transplantation

NEPHROLOGY DIALYSIS TRANSPLANTATION

NEPHROL DIAL TRANSPL

24

9

2773

2779

7

0931-0509

DOIhttps://doi.org/10.1093/ndt/gfp175



Conclusions. Coronary flow reserve was normal although baseline myocardial blood flow was increased in all CKD patients as compared to healthy controls. Peripheral endothelial dysfunction was detected in all patients. Our findings suggest that coronary perfusion and peripheral vascular function are disturbed by different mechanisms in patients with CKD.




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