Juhani Knuuti
MD, professor, Turku PET Centre
Research community or research topic
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
- Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain (2024) Biavati, F.; Saba, L.; Boussoussou, M.; Kofoed, K. F.; Benedek, T.; Donnelly, P.; Rodríguez-Palomares, J.; Erglis, A.; Štěchovský, C.; Šakalytė, G.; Čemerlić Ađić, N.; Gutberlet, M.; Dodd, J. D.; Diez, I.; Davis, G.; Zimmermann, E.; Kępka, C.; Vidakovic, R.; Francone, M.; Ilnicka-Suckiel, M.; Plank, F.; Knuuti, J.; Faria, R.; Schröder, S.; Berry, C.; Ruzsics, B.; Rieckmann, N.; Kubiak, C.; Hansen, K. S.; Müller-Nordhorn, J.; Maurovich-Horvat, P.; Sigvardsen, P. E.; Benedek, I.; Orr, C.; Valente, F. X.; Zvaigzne, L.; Suchánek, V.; Jankauskas, A.; Ađić, F.; Woinke, M.; Cadogan, D.; Lecumberri, I.; Thwaite, E.; Kruk, M.; Neskovic, A. N.; Mancone, M.; Kuśmierz, D.; Feuchtner, G.; Pietilä, M.; Ribeiro, V. G.; Drosch, T.; Delles, C.; Cau, R.; Fisher, M.; Merkely, B.; Kragelund, C.; Aurelian, R.; Kelly, S.; García Del Blanco, B.; Rubio, A.; Szilveszter, B.; Hove, J. D.; Rodean, I.; Regan, S.; Cuéllar Calabria, H.; Édes, I. F.; Larsen, L.; Hodas, R.; Napp, A. E.; Haase, R.; Feger, S.; Mohamed, M.; Serna-Higuita, L. M.; Neumann, K.; Dreger, H.; Rief, M.; Wieske, V.; Budoff, M. J.; Estrella, M.; Martus, P.; Bosserdt, M.; Dewey, M.; DISCHARGE Trial Group
(A1 Refereed original research article in a scientific journal)
- Daily standing time, dietary fiber, and intake of unsaturated fatty acids are beneficially associated with hepatic insulin sensitivity in adults with metabolic syndrome (2024)
- Frontiers in Endocrinology
Laine, Saara; Sjöros, Tanja; Garthwaite, Taru; Honka, Miikka-Juhani; Löyttyniemi, Eliisa; Eskola, Olli; Saarenhovi, Maria; Kallio, Petri; Koivumäki, Mikko; Vähä-Ypyä, Henri; Sievänen, Harri; Vasankari, Tommi; Hirvonen, Jussi; Laitinen, Kirsi; Houttu, Noora; Kalliokoski, Kari; Saunavaara, Virva; Knuuti, Juhani; Heinonen, Ilkka H.A.
(A1 Refereed original research article in a scientific journal)
- Determining Hemodynamically Significant Coronary Artery Disease : Patient-Specific Cutoffs in Quantitative Myocardial Blood Flow Using [15O]H2O PET Imaging (2024)
- Journal of Nuclear Medicine
Hoek, Roel; van Diemen, Pepijn A.; Raijmakers, Pieter G.; Driessen, Roel S.; Somsen, Yvemarie B. O.; de Winter, Ruben W.; Jukema, Ruurt A.; Twisk, Jos W. R.; Robbers, Lourens F. H. J.; van der Harst, Pim; Saraste, Antti; Lubberink, Mark; Sörensen, Jens; Knaapen, Paul; Knuuti, Juhani; Danad, Ibrahim
(A1 Refereed original research article in a scientific journal)
- Diagnostic Performance of Quantitative Perfusion Cardiac Magnetic Resonance Imaging in Patients with Prior Coronary Artery Disease (2024)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Hoek, R; Borodzicz-Jazdzyk, S; van Diemen, PA; Somsen, YBO; de Winter, RW; Jukema, RA; Twisk, JWR; Raijmakers, PG; Knuuti, J, Maaniitty, T; Underwood, SR; Nagel, E; Robbers, LFHJ; Demirkiran, A; von Bartheld, MB; Driessen, RS; Danad, I; Götte, MJW; Knaapen, P
(A1 Refereed original research article in a scientific journal)
- Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial (2024) Sykes, R.; Collison, D.; Merkely, B.; Kofoed, K. F.; Donnelly, P.; Rodríguez-Palomares, J.; Erglis, A.; Veselka, J.; Šakalytė, G.; Ađić, N. Č.; Gutberlet, M.; Dodd, J. D.; Diez, I.; Davis, G.; Zimmermann, E.; Kępka, C.; Vidakovic, R.; Francone, M.; Ilnicka-Suckiel, M.; Plank, F.; Knuuti, J.; Faria, R.; Schröder, S.; Berry, C.; Saba, L.; Ruzsics, B.; Rieckmann, N.; Kubiak, C.; Hansen, K. S.; Müller-Nordhorn, J.; Maurovich-Horvat, P.; Knudsen, A. D.; Benedek, I.; Orr, C.; Valente, F. X.; Zvaigzne, L.; Horváth, M.; Jankauskas, A.; Ađić, F.; Woinke, M.; Keane, S.; Lecumberri, I.; Thwaite, E.; Laule, M.; Kruk, M.; Zivanic, A.; Mancone, M.; Kuśmierz, D.; Feuchtner, G.; Pietilä, M.; Ribeiro, V. G.; Drosch, T.; Delles, C.; Porcu, M.; Fisher, M.; Bárány, T.; Sørum, C.; Aurelian, R.; Kelly, S.; Garcia Del Blanco, B.; Rubio, A.; Szilveszter, B.; Abdulla, J.; Rodean, I.; Regan, S.; Cuéllar Calabria, H.; Vecsey-Nagy, M.; Jurlander, B.; Hodas, R.; Feger, S.; Mohamed, M.; Serna-Higuita, L. M.; Neumann, K.; Dreger, H.; Rief, M.; Wieske, V.; Ferencik, M.; Estrella, M.; Bosserdt, M.; Martus, P.; Benedek, T.; Dewey, M.; DISCHARGE Trial Group
(A1 Refereed original research article in a scientific journal)
- Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT (2024)
- Journal of Human Hypertension
Norha, Jooa; Sjöros, Tanja; Garthwaite, Taru; Laine, Saara; Saarenhovi, Maria; Kallio, Petri; Laitinen, Kirsi; Houttu, Noora; Vähä-Ypyä, Henri; Sievänen, Harri; Löyttyniemi, Eliisa; Vasankari, Tommi; Knuuti, Juhani; Kalliokoski, Kari K.; Heinonen, Ilkka H. A.
(A1 Refereed original research article in a scientific journal)
- Evaluation of 18F FOL a PET tracer targeting folate receptor beta in a rat model of myocardial infarction (2024) Iqbal I; Liljenback H L; Andriana P A; Stahle M S; Virta J V; Herre E A H; Miner M W M; Anand A A; Kyto V K; Li X G L; Low P S L; Srinivasarao M S; Knuuti J K; Roivainen A R; Saraste A S
(Abstract)
- Explainable deep-learning-based ischemia detection using hybrid O-15 H2O perfusion positron emission tomography and computed tomography imaging with clinical data (2024)
- Journal of Nuclear Cardiology
Teuho, Jarmo; Schultz, Jussi; Klén, Riku; Juarez-Orozco, Luis Eduardo; Knuuti, Juhani; Saraste, Antti; Ono, Naoaki; Kanaya, Shigehiko
(A1 Refereed original research article in a scientific journal)
- Factors affecting the performance of a novel artificial intelligence-based coronary computed tomography-derived ischaemia algorithm (2024)
- European heart journal : imaging methods and practice
Kiatkittikul, Peerapon; Maaniitty, Teemu; Bär, Sarah; Nabeta, Takeru; Bax, Jeroen J; Saraste, Antti; Knuuti, Juhani
(A1 Refereed original research article in a scientific journal)
- Imaging of Myocardial αvβ3Integrin Expression for Evaluation of Myocardial Injury After Acute Myocardial Infarction (2024)
- Journal of Nuclear Medicine
Nammas, Wail; Paunonen, Christian; Teuho, Jarmo; Siekkinen, Reetta; Luoto, Pauliina; Käkelä, Meeri; Hietanen, Ari; Viljanen, Tapio; Dietz, Matthieu; Prior, John O.; Li, Xiang-Guo; Roivainen, Anne; Knuuti, Juhani; Saraste, Antti
(A1 Refereed original research article in a scientific journal)
