Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Dietary patterns from youth to adulthood and cognitive function in midlife: The cardiovascular risk in Young Finns StudyAdherence to risk-assessment protocols to guide computed tomography pulmonary angiography in patients with suspected pulmonary embolism (2023)
- NutritionEuropean Heart Journal - Quality of Care and Clinical Outcomes
- Evidence for protein leverage in a general population sample of children and adolescentsAfamin predicts the prevalence and incidence of nonalcoholic fatty liver disease (2023)
- European Journal of Clinical Nutrition
- Gene Set Based Integrated Methylome and Transcriptome Analysis Reveals Potential Molecular Mechanisms Linking Cigarette Smoking and Related DiseasesBody-mass index trajectories from childhood to mid-adulthood and their sociodemographic predictors: Evidence from the International Childhood Cardiovascular Cohort (i3C) Consortium (2023)
- OMICS
- Lipoprotein(a) in Youth and Prediction of Major Cardiovascular Outcomes in AdulthoodCase Fatality of Patients With Type 1 Diabetes After Myocardial Infarction (2023)
- CirculationDiabetes Care
- Neighbourhood deprivation in childhood and adulthood and risk of arterial stiffness: the Cardiovascular Risk in Young Finns study (2023)
- Blood Pressure
- Socioeconomic disadvantage and polygenic risk for high BMI magnify obesity risk across childhood: a longitudinal, population, cohort studyDecreasing severity of obesity from early to late adolescence and young adulthood associates with longitudinal metabolomic changes implicated in lower cardiometabolic disease risk (2023)
- Lancet Global HealthInternational Journal of Obesity
- Stress-Related Exhaustion, Polygenic Cognitive Potential, and Cognitive Test Performance - A General Population Study (2023)
- Cognitive Therapy and Research
- The Associations of Childhood Psychosocial Factors With Cognitive Function in Midlife-The Young Finns Study (2023)
- Neuropsychology
- The potential of intervening on childhood adversity to reduce socioeconomic inequities in body mass index and inflammation among Australian and UK children: A causal mediation analysis (2023)
- Journal of Epidemiology and Community HealthHuman Fertility
- Tracking of apolipoprotein B levels measured in childhood and adolescence: systematic review and meta-analysisGene set analysis of transcriptomics data identifies new biological processes associated with early markers of atherosclerosis but not with those of osteoporosis: Atherosclerosis-osteoporosis co/multimorbidity study in the Young Finns Study (2023)
- European Journal of PediatricsAtherosclerosis
- Impact of within-visit systolic blood pressure change patterns on blood pressure classification: the Cardiovascular Risk in Young Finns Study (2022)
- (2022)
- Clinical Chemistry and Laboratory Medicine
- (2022)
- EClinicalMedicine
- (2022)
- Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events (2022)
- New England Journal of Medicine
- (2022)
- Dietary Saturated Fat and Bone Health in Young Adults: The Young Finns Cohort (2022)
- Calcified Tissue International
- Does being conceived by assisted reproductive technology influence adult quality of life? (2022)
- (2022)
- (2022)
- European Journal of Preventive Cardiology